Intra-Species Diversity between Seven Bifidobacterium adolescentis Strains Identified by Genome-Wide Tiling Array Analysis
Intra-Species Diversity between Seven Bifidobacterium adolescentis Strains Identified by Genome-Wide Tiling Array Analysis
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DOI：
10.1271/bbb.80843
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发表时间：
2009-06-01
影响因子：
1.6
通讯作者：
Suzuki, Tohru
中科院分区：
文献类型：
--
作者：
Yasui, Kazumasa;Tabata, Mototsugu;Suzuki, Tohru
使用根据 ATCC15703 全基因组序列设计的平铺阵列对六种青春双歧杆菌菌株 JCM1275、JCM1251、JCM7044、JCM7045、JCM7046 和 9-124 进行分析。结果证明了缺失簇以及单基因突变和缺失。大多数缺失涉及多糖和细胞表面生物发生的基因。提出了说明缺失和突变的树状图，并讨论了青春双歧杆菌的进化。
Six Bifidobacterium adolescentis strains, JCM1275, JCM1251, JCM7044, JCM7045, JCM7046, and 9-124, were analyzed using a tiling array designed according to the full genome sequence of ATCC15703. The results demonstrated deletion clusters along with single-gene mutations and deletions. Most deletions concerned genes involved in polysaccharide and cell-surface biogenesis. A dendrogram illustrating the deletions and mutations is presented and the evolution of B. adolescentis is discussed.