Lymphocyte transformation studies in suspected hypersensitivity to trimethoprim‐sulphamethoxazole

Lymphocyte transformation studies in suspected hypersensitivity to trimethoprim‐sulphamethoxazole
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疑似甲氧苄氨嘧啶-磺胺甲恶唑过敏者的淋巴细胞转化研究

DOI:
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发表时间:
1983
期刊:
Clinical allergy
影响因子:
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通讯作者:
Swawn McPHILLIPS
Swawn McPHILLIPS
中科院分区:
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文献类型:
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作者:
R. Warrington;P. Sauder;Swawn McPHILLIPS

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In a group of patients with suspected and probable adverse skin reactions to trimethoprim‐sulphamethoxazole, the lymphocyte transformation test (LTT) was positive in approximately 60% of subjects tested. Levels of stimulation in the majority of cases were low, probably reflecting either use of inappropriate stimulatory forms of the drug or lack of marked reactivity. Since there appeared to be a correlation between peak stimulatory index and duration of the rash, the latter explanation appeared more likely.