The mechanism of respiratory arrest in inspiratory loading and hypoxemia.
The mechanism of respiratory arrest in inspiratory loading and hypoxemia.
复制标题
吸气负荷和低氧血症导致呼吸骤停的机制。
DOI：
10.1164/ajrccm/141.4_pt_1.933
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发表时间：
1990
期刊：
影响因子：
--
通讯作者：
Wood,LD
中科院分区：
文献类型：
--
作者：
Yanos,J;Keamy3rd,MF;Leisk,L;Hall,JB;Walley,KR;Wood,LD
Respiratory arrests occur in the clinical settir. g of respiratory failure, but the mechanism is unclear. We used a dog model with increased inspiratory resistance and hypoxemia to explore the cause. Wehypothesized that respiratory muscle fatigue (RMF) played a role in these respiratory arrests, and that the combination of hypoxia and resistive loading would produce respiratory arrest by the mechanism of RMF. Our preparation had transdiaphragmatic pressures that were 40% of maximum (Pdimax= 46.3±10.0 cm H, O) and progressive hypoxia resulting in a final arterial
