Relationship Dynamics and Partner Beliefs About Viral Suppression: A Longitudinal Study of Male Couples Living with HIV/AIDS (The Duo Project).
Relationship Dynamics and Partner Beliefs About Viral Suppression: A Longitudinal Study of Male Couples Living with HIV/AIDS (The Duo Project).
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DOI：
10.1007/s10461-016-1423-9
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发表时间：
2016-07
影响因子：
4.4
通讯作者：
Johnson MO
中科院分区：
文献类型：
--
作者：
Conroy AA;Gamarel KE;Neilands TB;Dilworth SE;Darbes LA;Johnson MO
对伴侣的病毒抑制的准确信念对艾滋病毒预防和护理很重要。我们拟合多水平混合效应logistic回归模型，以检查伴侣的病毒抑制信念和客观的HIV RNA病毒载量测试之间的关联，以及随着时间的推移，关系动态是否与准确的病毒抑制信念相关。至少有一名艾滋病毒阳性伴侣接受抗逆转录病毒治疗的男性夫妇（N=266对夫妇）在两年内完成了五次评估。在407名艾滋病毒阳性伴侣中，有一半的人病毒受到抑制。在40%对病毒载量信念不准确的人中，80%的人认为他们的伴侣受到了抑制。随着时间的推移，拥有准确的病毒载量信念的几率逐渐下降（OR=0.83; p= 0.042）。夫妻间的二元调整（OR=0.66; p<0.01）和承诺（OR=0.82; p= 0.022）差异与准确的病毒载量信念呈负相关。对伴侣病毒载量的信念可能会影响性决策和社会支持。基于夫妇的方法是必要的，以提高知识的合作伙伴的病毒载量。
Accurate beliefs about partners’ viral suppression are important for HIV prevention and care. We fit multilevel mixed effects logistic regression models to examine associations between partners’ viral suppression beliefs and objective HIV RNA viral load tests, and whether relationship dynamics were associated with accurate viral suppression beliefs over time. Male couples (N=266 couples) with at least one HIV-positive partner on antiretroviral therapy completed five assessments over two years. Half of the 407 HIV-positive partners were virally suppressed. Of the 40% who had inaccurate viral load beliefs, 80% assumed their partner was suppressed. The odds of having accurate viral load beliefs decreased over time (OR=0.83; p=.042). Within-couple differences in dyadic adjustment (OR=0.66; p<.01) and commitment (OR=0.82; p=.022) were negatively associated with accurate viral load beliefs. Beliefs about a partner's viral load may factor into sexual decision-making and social support. Couple-based approaches are warranted to improve knowledge of partners’ viral load.