Thermally dynamic examination of local order in nanocrystalline hydroxyapatite
Thermally dynamic examination of local order in nanocrystalline hydroxyapatite
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DOI：
10.1016/j.jssc.2022.123474
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发表时间：
2022-08-13
影响因子：
3.3
通讯作者：
Rogers，Keith D.
中科院分区：
文献类型：
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作者：
Arnold，Emily L.;Gosling，Sarah;Rogers，Keith D.
骨的主要矿物成分是羟基磷灰石，这是一种常见的纳米晶材料，对于那些试图表征它的人来说存在许多挑战。在这里，使用X射线全散射分析合成样品的局部结构，以更好地理解羟基磷灰石的纳米晶性质。在25 °C至800 °C的热处理期间动态测量两个样品，并使用小箱建模进行分析。在关键温度下连续测量的分析表明，时间和温度之间存在显着的关系，这表明一个过程发生得比热膨胀更慢。这表明在550 °C和575 °C之间B型CO32−取代减少，而在750 °C以上A型CO32−取代增加。更好地了解这种复杂的生物矿物在热处理过程中的局部，中间和远程顺序可以在几个部门中感兴趣，例如在法医，生物医学和临床环境中研究植入物涂层和骨骼疾病，包括骨质疏松症和骨关节炎。
The main mineral component of bone is hydroxyapatite, a commonly nanocrystalline material which presents many challenges for those trying to characterize it. Here, local structure is analyzed using X-ray total scattering for synthetic samples, to enable a better understanding of the nanocrystalline nature of hydroxyapatite. Two samples were measured dynamically during heat treatment from 25 °C to 800 °C, and were analyzed using small box modelling. Analysis of sequential measurements when dwelling at key temperatures showed a significant relationship between time and temperature, indicating a process occurring more slowly than thermal expansion. This indicates a decrease in B-type CO32−substitution between 550 °C and 575 °C and an increase in A-type CO32−substitution above 750 °C. A greater understanding of local, intermediate, and long-range order of this complex biomineral during heat treatment can be of interest in several sectors, such as in forensic, biomedical and clinical settings for the study of implant coatings and bone diseases including osteoporosis and osteoarthritis.