Mortality, morbidity, and disease severity of patients with aspiration pneumonia.
Mortality, morbidity, and disease severity of patients with aspiration pneumonia.
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DOI：
10.1002/jhm.1996
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发表时间：
2013-02
影响因子：
2.6
通讯作者：
Dean, Nathan C.
中科院分区：
文献类型：
--
作者：
Lanspa, Michael J.;Jones, Barbara E.;Brown, Samuel M.;Dean, Nathan C.
吸入性肺炎是一种常见综合征，但其特征不如其他肺炎综合征。我们描述了大量吸入性肺炎患者。在这项回顾性人群研究中，我们查询了 1996 年至 2006 年大学附属三级医院的电子病历。患者最初通过 ICD-9 代码 507.x 进行识别；随后的医生图表审查排除了吸入性肺炎患者和没有X线确诊的患者。将社区获得性吸入性肺炎患者与同期社区获得性肺炎 (CAP) 患者进行比较。我们将 CURB-65 预测死亡率与实际 30 天死亡率进行了比较。我们发现了 628 名吸入性肺炎患者，其中 510 名是社区获得性肺炎。中位年龄为 77 岁，30 天死亡率为 21%。与 CAP 患者相比，社区获得性吸入性肺炎患者住院（99% vs. 58%）和 ICU 入住（38% vs. 14%）的频率更高，查尔森合并症指数更高（3 vs. 1），“不复苏/插管”命令的发生率更高（24% vs. 11%）。 CURB-65 对吸入性肺炎患者死亡率的预测效果较差（AUC 0.66）。与 CAP 患者相比，社区获得性吸入性肺炎患者年龄更大、合并症更多，死亡率也更高，即使在调整了年龄和合并症后也是如此。 CURB-65 对该人群的死亡率预测不佳。
Aspiration pneumonia is a common syndrome, although less well characterized than other pneumonia syndromes. We describe a large population of patients with aspiration pneumonia. In this retrospective population study, we queried the electronic medical record at a tertiary-care, university-affiliated hospital from 1996–2006. Patients were initially identified by ICD-9 code 507.x; subsequent physician chart review excluded patients with aspiration pneumonitis and those without a confirmatory radiograph. Patients with community-acquired aspiration pneumonia were compared to a contemporaneous population of community-acquired pneumonia (CAP) patients. We compared CURB-65 predicted mortality with actual 30-day mortality. We identified 628 patients with aspiration pneumonia, of which 510 were community-acquired. Median age was 77, with 30-day mortality of 21%. Compared to CAP patients, patients with community-acquired aspiration pneumonia had more frequent inpatient admission (99% vs. 58%) and ICU admission (38% vs. 14%), higher Charlson comorbidity index (3 vs. 1), and higher prevalence of “do not resuscitate/intubate” orders (24% vs. 11%). CURB-65 predicted mortality poorly in aspiration pneumonia patients (AUC 0.66). Patients with community-acquired aspiration pneumonia are older, have more comorbidities, and demonstrate higher mortality than CAP patients, even after adjustment for age and comorbidities. CURB-65 poorly predicts mortality in this population.
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影响因子：
7.2
作者：
DEYO, RA;CHERKIN, DC;CIOL, MA
通讯作者：
CIOL, MA
影响因子：
5.9
作者：
BARTLETT, JG;GORBACH, SL;FINEGOLD, SM
通讯作者：
FINEGOLD, SM
DOI：
10.1164/rccm.200602-177oc
发表时间：
2006-12-01
影响因子：
24.7
作者：
Espana, Pedro P.;Capelastegui, Alberto;Quintana, Jose M.
通讯作者：
Quintana, Jose M.
影响因子：
--
作者：
GONZALEZC, CL;CALIA, FM
通讯作者：
CALIA, FM
影响因子：
1.2
作者：
Heppner, H. J.;Sehlhoff, B.;Thiem, U.
通讯作者：
Thiem, U.