Controversies in defining cardiac antibody-mediated rejection: Need for updated criteria

Controversies in defining cardiac antibody-mediated rejection: Need for updated criteria
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DOI:
10.1016/j.healun.2009.10.016
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发表时间:
2010-04-01
影响因子:
8.9
通讯作者:
Hammond, M. Elizabeth H.
Hammond, M. Elizabeth H.
中科院分区:
医学1区
文献类型:
--
作者:
Kfoury, Abdallah G.;Hammond, M. Elizabeth H.

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近年来,随着国际心肺移植学会的正式认可,人们对心脏抗体介导的排斥反应(AMR)的重要性的认识不断提高。关于心脏AMR的病理学和临床行为的新见解与当前的诊断指南不一致。这一观点探讨了心脏AMR中一些有争议和未解决的问题,因为移植界正在采取具体措施更新其定义标准。J Heart Lung Transplant 2010;29:389-394(C)2010年国际心肺移植学会。All rights reserved.
Recent years have seen a rising awareness of the significance of cardiac antibody-mediated rejection (AMR) as a result of its formal recognition by the International Society for Heart and Lung Transplantation. New insights on the pathology and clinical behavior of cardiac AMR are at odds with current diagnostic guidelines. This perspective examines some of the contentious and unresolved issues in cardiac AMR as the transplant community makes concrete steps towards updating its defining criteria. J Heart Lung Transplant 2010;29:389-394 (C) 2010 International Society for Heart and Lung Transplantation. All rights reserved.