PROPER USE OF SKIN-TESTS WITH FOOD EXTRACTS IN DIAGNOSIS OF HYPERSENSITIVITY TO FOOD IN CHILDREN
PROPER USE OF SKIN-TESTS WITH FOOD EXTRACTS IN DIAGNOSIS OF HYPERSENSITIVITY TO FOOD IN CHILDREN
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DOI：
10.1111/j.1365-2222.1977.tb01466.x
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发表时间：
1977-01-01
期刊：
影响因子：
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通讯作者：
MAY, CD
中科院分区：
文献类型：
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作者：
BOCK, SA;BUCKLEY, J;MAY, CD
将由分级量的食物提取物引起的皮肤反应与双盲食物挑战和白细胞组胺体外释放的结果进行比较。使用1：20 wt/vol浓度的食物提取物通过穿刺技术进行的皮肤试验中3 mm或更大的伤痕反应表明超敏反应的程度可能与对食物的临床显著超敏反应相关。正确使用这种简单的技术将有助于准确诊断儿童食物过敏，通过确定其中所有的食物激发阳性反应的群体将被发现。双盲食物激发是必不可少的，以建立对食物过敏症状的诊断。
Cutaneous reactions evoked by graded amounts of food extracts were compared with results of double-blind food challenge and in vitro release of histamine from leukocytes. A 3 mm or greater weal reaction in skin tests by puncture technique using food extracts of 1:20 wt/vol concentration indicated the degree of hypersensitivity likely to be associated with clinically significant hypersensitivity reactions to food. Proper use of this simple technique will facilitate accurate diagnosis of food hypersensitivity in children by identifying the group among whom all positive reactions to food challenges will be found. Double-blind-food challenge is essential to establish a diagnosis of symptomatic hypersensitivity to food.