DNA Methylation and Chromatin Regulation during Fleshy Fruit Development and Ripening.
DNA Methylation and Chromatin Regulation during Fleshy Fruit Development and Ripening.
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DOI：
10.3389/fpls.2016.00807
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发表时间：
2016
影响因子：
5.6
通讯作者：
Seymour GB
中科院分区：
文献类型：
--
作者：
Gallusci P;Hodgman C;Teyssier E;Seymour GB
果实成熟是一个发育过程，导致花的叶状心皮器官成为成熟的子房，为种子的传播做好准备。肉质水果的成熟涉及深刻的代谢相变，受到严格的激素和基因控制。这项工作回顾了我们对果实成熟表观遗传调控的理解的最新进展。我们首先描述组蛋白翻译后修饰和染色质结构重塑过程的最新进展及其对果实发育和成熟的影响。然而，综述的重点是 DNA 甲基化水平的变化对成熟相关基因表达的影响。这包括在没有 DNA 序列改变的情况下导致可遗传表型变异的那些变化，以及它们的启动和维持机制。文献中描述的大多数研究都涉及番茄，但越来越多的证据表明其他水果物种的成熟也可能受到表观遗传的控制。我们讨论表观遗传差异如何为育种和作物改良提供新目标。
Fruit ripening is a developmental process that results in the leaf-like carpel organ of the flower becoming a mature ovary primed for dispersal of the seeds. Ripening in fleshy fruits involves a profound metabolic phase change that is under strict hormonal and genetic control. This work reviews recent developments in our understanding of the epigenetic regulation of fruit ripening. We start by describing the current state of the art about processes involved in histone post-translational modifications and the remodeling of chromatin structure and their impact on fruit development and ripening. However, the focus of the review is the consequences of changes in DNA methylation levels on the expression of ripening-related genes. This includes those changes that result in heritable phenotypic variation in the absence of DNA sequence alterations, and the mechanisms for their initiation and maintenance. The majority of the studies described in the literature involve work on tomato, but evidence is emerging that ripening in other fruit species may also be under epigenetic control. We discuss how epigenetic differences may provide new targets for breeding and crop improvement.