Serum thymus and activation-regulated chemokine levels before and after treatment for pruritic scabies.
Serum thymus and activation-regulated chemokine levels before and after treatment for pruritic scabies.
复制标题
瘙痒性疥疮治疗前后的血清胸腺和活化调节趋化因子水平。
DOI：
10.1111/jdv.16698
复制
发表时间：
2020
期刊：
影响因子：
--
通讯作者：
et al.
中科院分区：
文献类型：
--
作者：
Arakawa;Tamagawa-Mineoka;et al.
我亲爱的编辑，我的疮疮通常发生在老年患者中，经典的疮疮可能类似于Th2免疫相关的皮肤病，如特应性皮炎(AD)和结节性瘙痒(PN)。1血清免疫球蛋白E(IgE)水平在溃疡病感染期间有升高的报道，治疗后有所下降。2、3、4在此，我们首次报告一例瘙痒性溃烂，患者血清胸腺和活化调节趋化因子(TARC)水平升高，治疗后血清胸腺和活化调节趋化因子(TARC)水平下降。根据病人的临床病程--在此过程中，除治疗麻疹外，没有采用其他治疗方法--他的皮肤症状的改善以及血清TARC和IgE水平的降低被认为是由于治疗溃疡。His-IgE水平在溃疡病感染后升高，经伊维菌素治疗后轻度下降。溃疡有两种常见的亚型：经典型的和结痂的。1、5典型溃烂的皮肤表现包括洞穴和红斑丘疹/结节。
Abstract I Dear Editor, i Scabies commonly occurs in elderly patients, and classic scabies can resemble Th2 immunity-related dermatological diseases, such as atopic dermatitis (AD) and prurigo nodularis (PN). 1 Elevated serum immunoglobulin E (IgE) levels have been reported during scabies infections, which reduced after the scabies was treated. 2, 3, 4 Here, we report, for the first time, a case of pruritic scabies, involving elevated serum thymus and activation-regulated chemokine (TARC) levels, which decreased after the scabies was treated. Based on the patient's clinical course, in which no treatments other than the scabies treatment were introduced, the improvement of his skin symptoms and reductions in his serum TARC and IgE levels were considered to have been due to the scabies treatment. His IgE levels were increased by the scabies infection and mildly decreased after the ivermectin treatment. gl There are two common subtypes of scabies: classic and crusted scabies. 1, 5 The skin manifestations of classic scabies include burrows and erythematous papules/nodules.[Extracted from the article]