Antisperm antibodies in cryptorchidism before and after surgery
Antisperm antibodies in cryptorchidism before and after surgery
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DOI：
10.1016/s0022-5347(01)62428-5
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发表时间：
1998-11-01
影响因子：
6.6
通讯作者：
Bellastella, A
中科院分区：
文献类型：
--
作者：
Sinisi, AA;Pasquali, D;Bellastella, A
目的：我们验证了血清抗精子抗体的患病率在一个大的隐睾症男孩的诊断，并确定是否可能受到影响orchiopexy.Materials和方法：我们前瞻性地评估了血清抗精子抗体在186和23个男孩0.67至14.25岁的单侧和双侧隐睾症，分别在手术前，3，12和24个月后。诊断时坦纳分期1级188例，2级21例，3级21例。在2年的随访中，23名男孩进入青春期。共111名正常青春期前（坦纳1期）和54名青春期（坦纳2或3期）男孩作为对照。结果：隐睾患儿中29例（13.8%）抗精子抗体阳性，其中青春期前21例（11.1%），青春期8例（38%），两组间差异有显著性（χ 2检验，P < 0.01）。
Purpose: We verified the prevalence of serum antisperm antibodies at diagnosis in a large group of cryptorchid boys, and determined whether it may be influenced by orchiopexy.Materials and Methods: We prospectively evaluated serum antisperm antibodies in 186 and 23 boys 0.67 to 14.25 years old with unilateral and bilateral cryptorchidism, respectively, before, and 3, 12 and 24 months after surgery. At diagnosis Tanner stage was 1 and 2 or 3 in 188 and 21 cases, respectively. During the 2-year followup 23 boys entered puberty. A total of 111 normal prepubertal (Tanner stage 1) and 54 pubertal (Tanner stage 2 or 3) boys served as controls. Antisperm antibodies were detected using the tray agglutination and indirect immunobead tests.Results: At diagnosis 29 cryptorchid boys (13.8%) were antisperm antibody positive, including 21 of the 188 prepubertal (11.1%) and 8 of the 21 pubertal (38%) boys (significantly different, chi-square test p