Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis
Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis
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DOI：
10.1007/978-1-4471-6729-7_24
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发表时间：
2015-05-15
期刊：
影响因子：
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通讯作者：
Vandergriff T
中科院分区：
文献类型：
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作者：
Klimas N;Quintanilla-Dieck J;Vandergriff T
多形性红斑最极端的形式传统上分为中毒性表皮坏死松解和史蒂文斯-约翰逊综合征。这两种危及生命的皮肤病现在被认为是同一疾病谱系的一部分。它们可以通过临床和组织学标准来区分。我们现在还可以预测哪些病人的预后最不可靠。多种药物的治疗并不完美，但比以往任何时候都有更好的机会获得良好的结果。
Erythema multiforme in its most extreme form has traditionally been divided between toxic epidermal necrolysis and Stevens-Johnson Syndrome. These two life-threatening skin diseases are now considered part of the same spectrum of disease. They can be differentiated by clinical and histological criteria. We can also now predict which patients are apt to have the most guarded prognosis. Treatment by multiple agents is imperfect, but offers a better chance of a good outcome than ever before.