EXPIRATORY EFFECTS OF BRIEF CAROTID-SINUS NERVE AND CAROTID-BODY STIMULATIONS
EXPIRATORY EFFECTS OF BRIEF CAROTID-SINUS NERVE AND CAROTID-BODY STIMULATIONS
复制标题
DOI：
10.1016/0034-5687(76)90009-8
复制
发表时间：
1976-01-01
期刊：
影响因子：
--
通讯作者：
ELDRIDGE, FL
中科院分区：
文献类型：
--
作者：
ELDRIDGE, FL
在麻醉猫中测定对颈动脉窦神经短暂间歇性电刺激或颈动脉体化学刺激的呼气反应，直接测量为通气量和内部肋间或腹部肌肉肌电图活动。呼气期间给予的刺激具有特定的呼气效果，表现为呼气持续时间增加、呼气肌肉活动增加和呼气深度增加。刺激出现的时间越晚，所有效果就越大。迷走神经切断对反应没有影响，并且在 C7-T1 脊髓切断后反应持续时间仍然存在。呼气刺激对呼气的影响显然与吸气过程中给予刺激对吸气的影响相似。该机制可能在脑干水平上发挥作用。由于对相同刺激的反应潜伏期比吸气反应长得多，因此途径必定不同。
The expiratory response, measured directly as ventilatory volume and as internal intercostal or abdominal muscle electromyogram activity, to brief intermittent electrical stimulation of the carotid sinus nerve or chemical stimulation of the carotid body was determined in anesthetized cats. Stimuli given during expiration had a specific expiratory effect, manifested by increased expiratory duration, increased activity of expiratory muscles and increased depth of expiration. The later in expiration the stimulus was exhibited, the greater all effects became. Vagal section had no effect on the response and the duration of response persisted after spinal cord section at C7-T1. Expiratory stimulations apparently have effects on expiration similar to those on inspiration from stimulations given during inspiration; the mechanism probably operates at a brain stem level. Because the latency of the response was much longer than the inspiratory response to the same stimuli, the pathway must be different.