1774P The study of physical and mental distress among cancer patients during the COVID-19 epidemic
1774P The study of physical and mental distress among cancer patients during the COVID-19 epidemic
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DOI：
10.1016/j.annonc.2020.08.1838
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发表时间：
2020-09-22
影响因子：
50.5
通讯作者：
Khouchani M
中科院分区：
文献类型：
--
作者：
Naqos N;Khouchani M
背景2019年12月，检测到由新型冠状病毒引起的人类呼吸道感染疫情。它的特点是人与人之间的快速传播，导致大流行病的蔓延。癌症护理实践范式在这段时间内发生了巨大变化，因此，癌症患者可能会表现出心理困难。本研究的目的是评估癌症患者在这场大流行期间的身体和精神痛苦的强度。方法从2020年3月23日至5月11日，在马拉喀什大学医院肿瘤中心住院接受化疗的123名癌症患者被纳入研究。该小组由68名男性和55名女性组成。关于癌症的初始位置，分布如下：10例乳腺癌和妇科癌，19例胃肠癌，52例头颈癌，5例泌尿系统癌，28例肺癌和9例肉瘤。20例患者有精神病史。其中11人有抑郁症史。5例患者有酒精中毒的概念。4例患者有焦虑症病史。心理困扰的评估进行了使用2个量表：1。医院焦虑抑郁量表（HADS）2。结果HADS结果显示，焦虑77例（62%），抑郁67例（54%）。对于焦虑和抑郁，性别差异无统计学意义（卡方检验，P= 0.47）。有精神病史和无精神病史的患者之间无差异（P= 0，39）。对于ESAS，最常见的症状是财务困境（4;四分位数范围0-7）。而所有ESAS症状评估评分均为中度。大多数患者表示担心自己（90%）或家人（85%）被感染，以及由于延迟治疗而导致癌症进展（95%）。结论在COVID-19爆发期间，我们研究中的绝大多数癌症患者（超过一半）出现了焦虑，抑郁和对COVID-19感染的恐惧。这些结果意味着，在疫情期间随访的癌症患者需要认真的心理支持，重点是与COVID-19相关的恐惧。
BackgroundIn December 2019, an outbreak of respiratory infection in humans caused by a novel coronavirus was detected. It is characterized by rapid human-to-human transmission leading to a pandemic spread. Cancer care practice paradigms have drastically changed during this time and, consequently, cancer patients may exhibit psychological difficulties. The purpose of this study is to assess the intensity of physical and mental distress among cancer patients during this pandemic.Methods123 cancer patients hospitalised to receive chemotherapy at the oncology centre of the University Hospital of Marrakech were included from 23 March to 11 May 2020. This group consisted of 68 men and of 55 women. Regarding the initial location of the cancer, the distribution was as follows: 10 cancers of breast and gynaecological origin, 19 gastrointestinal, 52 head and neck cancers, 5 urological, 28 pulmonary cancers and 9 sarcoma. Twenty patients had a psychiatric history. Of these, 11 had a history of depression. In 5 patients, there was the notion of alcoholism. Four patients had a history of anxiety disorders. The assessment of psychological distress was carried out using 2 scales: 1. Hospital Anxiety and Depression Scale (HADS) 2. the Edmonton Symptom Assessment System Scale (ESAS).ResultsThe results of HADS showed 77 (62%) patients and 67 (54%) patients had anxiety and depression, respectively. For both anxiety and depression, the gender difference was not statistically significant (chi-square test, P= 0.47). There was no difference between patients with a psychiatric history and those without (P= 0, 39). For the ESAS, the most expressed symptom was financial distress (4; interquartile range 0-7). whereas all ESAS symptom assessment scores were moderate. The majority of patients expressed their worry about being infected themselves (90%) or their family (85%), and of cancer progression due to delayed treatment (95%).ConclusionsDuring the outbreak of COVID-19, the vast majority of cancer patients (more than half) in our study developed anxiety, depression and fear of COVID-19 infection. These results imply that cancer patients followed during the epidemic require serious psychosocial support focused on COVID-19-related fears.