Prognostic Models: A Methodological Framework and Review of Models for Breast Cancer

Prognostic Models: A Methodological Framework and Review of Models for Breast Cancer
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DOI:
10.1080/07357900802572110
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发表时间:
2009-01-01
影响因子:
2.4
通讯作者:
Altman, Douglas G.
Altman, Douglas G.
中科院分区:
医学4区
文献类型:
--
作者:
Altman, Douglas G.

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预后模型广泛用于癌症中,用于研究与多个患者和疾病特征相关的患者结果。这样的模型可以允许将患者(合理地)可靠地分类为具有不同症状的两个或更多个组。特别值得关注的是,确定预后良好的患者,辅助治疗不会(成本)受益,或预后不良的患者,更积极的辅助治疗将不合理(1)。
Prognostic models are widely used in cancer for investigating patient outcome in relation to multiple patient and disease characteristics. Such a model may allow the (reasonably) reliable classification of patients into two or more groups with different prognoses. It may be of particular interest to identify patients with a good prognosis that adjuvant therapy would not be (cost-)beneficial, or a group with a poor prognosis that more aggressive adjuvant therapy would not be justified (1).