Mycoplasma pneumoniae infections, 11 countries in Europe and Israel, 2011 to 2016
Mycoplasma pneumoniae infections, 11 countries in Europe and Israel, 2011 to 2016
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DOI：
10.2807/1560-7917.es.2020.25.2.1900112
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发表时间：
2020-01-16
期刊：
影响因子：
19
通讯作者：
McMenamin, Jim
中科院分区：
文献类型：
--
作者：
Beeton, Michael L.;Zhang, Xu-Sheng;McMenamin, Jim
背景资料：肺炎支原体是社区获得性肺炎的主要原因，以前描述的大流行每4至7年发生一次。目的：更好地了解用于检测M的诊断方法。pneumoniae;为了更好地了解M.肺炎检测和监测;确定流行病;确定每个年龄组的检测数量，阳性检测的年龄人口统计学，流行病的同时发生和跨地理区域的年高峰;以及确定地理位置对流行病时间的影响。研究方法：2016年5月，向ESCMID支原体和衣原体感染研究组的国家或区域负责人发送了一份调查问卷，该研究组在欧洲和以色列的17个国家开展，回顾性地要求提供关于支原体的详细信息。2011年1月至2016年4月的肺炎阳性样本。移动流行病的方法被用来确定流行期和国家纬度的影响，在调查的五个时期。结果：12个国家的代表提供了M.肺炎感染，占95，666个阳性样本。自2013年以来，两个实验室启动了常规大环内酯类耐药性检测。在2011年至2016年期间，确定了三次流行病：2011/12，2014/15和2015/16。M.肺炎阳性标本呈三种模式。在流行年份，注意到国家纬度和流行期开始的日历周之间的关联。结论：观察到流行病和纬度之间的关联。在阳性病例的年龄分布以及使用的检测方法和实践方面存在差异。注意到缺乏大环内酯类耐药性监测。
Background: Mycoplasma pneumoniae is a leading cause of community-acquired pneumonia, with large epidemics previously described to occur every 4 to 7 years. Aim: To better understand the diagnostic methods used to detect M. pneumoniae; to better understand M. pneumoniae testing and surveillance in use; to identify epidemics; to determine detection number per age group, age demographics for positive detections, concurrence of epidemics and annual peaks across geographical areas; and to determine the effect of geographical location on the timing of epidemics. Methods: A questionnaire was sent in May 2016 to Mycoplasma experts with national or regional responsibility within the ESCMID Study Group for Mycoplasma and Chlamydia Infections in 17 countries across Europe and Israel, retrospectively requesting details on M. pneumoniae-positive samples from January 2011 to April 2016. The Moving Epidemic Method was used to determine epidemic periods and effect of country latitude across the countries for the five periods under investigation. Results: Representatives from 12 countries provided data on M. pneumoniae infections, accounting for 95,666 positive samples. Two laboratories initiated routine macrolide resistance testing since 2013. Between 2011 and 2016, three epidemics were identified: 2011/12, 2014/15 and 2015/16. The distribution of patient ages for M. pneumoniae-positive samples showed three patterns. During epidemic years, an association between country latitude and calendar week when epidemic periods began was noted. Conclusions: An association between epidemics and latitude was observed. Differences were noted in the age distribution of positive cases and detection methods used and practice. A lack of macrolide resistance monitoring was noted.