Functional integration between defence and IRE1-mediated ER stress response in rice.
Functional integration between defence and IRE1-mediated ER stress response in rice.
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DOI：
10.1038/srep00670
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发表时间：
2012
影响因子：
4.6
通讯作者：
Takaiwa, Fumio
中科院分区：
文献类型：
--
作者：
Hayashi, Shimpei;Wakasa, Yuhya;Takaiwa, Fumio
内质网（ER）内的条件影响大多数通过内质网的分泌蛋白。因此，真核细胞必须在内质网应激反应（改变内质网的条件）和其他与蛋白质分泌相关的考虑之间取得平衡。本文描述了水稻内质网胁迫与防御反应之间的相互作用。OsWRKY45编码一种在水杨酸（SA）介导的防御中起核心作用的转录因子，其表达可由内质网应激诱导。此外，由应激传感器IRE1介导的内质网应激反应降低了一些编码致病相关（PR）分泌蛋白的基因的表达。SA和内质网应激反应的同时激活可抑制内质网应激反应基因（OsWRKY45除外）的诱导和PR基因表达的降低。这些发现表明植物的防御和内质网应激反应之间存在功能整合。
Conditions within the endoplasmic reticulum (ER) influence most secretory proteins that pass through the ER. Therefore, eukaryotic cells must strike a balance between the ER stress response, which changes the conditions in the ER, and other considerations associated with protein secretion. Here, an interaction between the ER stress and defence responses in rice is described. Expression of OsWRKY45, which encodes a transcription factor that plays a central role in defence mediated by salicylic acid (SA), is induced by ER stress. Additionally, expression of some genes encoding pathogenesis-related (PR) secretory proteins is reduced by the ER stress response mediated by the stress sensor IRE1. Concomitant activation of the SA and ER stress responses suppresses the induction of ER stress-responsive genes, with the exception of OsWRKY45, and the reduction of PR gene expression. These findings demonstrate a functional integration between the defence and ER stress responses in plants.
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影响因子：
4.9
作者：
Takahashi, Hideyuki;Kawakatsu, Taiji;Takaiwa, Fumio
通讯作者：
Takaiwa, Fumio
影响因子：
64.5
作者：
Yoshida, H;Matsui, T;Mori, K
通讯作者：
Mori, K
影响因子：
7.4
作者：
Vitale, A;Ceriotti, A
通讯作者：
Ceriotti, A
影响因子：
7.2
作者：
Wakasa, Yuhya;Yasuda, Hiroshi;Takaiwa, Fumio
通讯作者：
Takaiwa, Fumio
影响因子：
3.7
作者：
Moreno AA;Mukhtar MS;Blanco F;Boatwright JL;Moreno I;Jordan MR;Chen Y;Brandizzi F;Dong X;Orellana A;Pajerowska-Mukhtar KM
通讯作者：
Pajerowska-Mukhtar KM