Soft tissue giant cell tumor of low malignant potential.
Soft tissue giant cell tumor of low malignant potential.
复制标题
低度恶性潜能的软组织巨细胞瘤。
DOI：
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发表时间：
2004
期刊：
影响因子：
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通讯作者：
R. Tanino
中科院分区：
文献类型：
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作者：
Kota Icihikawa;R. Tanino
软组织巨细胞瘤（Giant cell tumor of soft tissue, GCT-ST）是一种罕见的肿瘤，由Salm和Sissons于1972年首次描述，gucion和Enzinger紧随其后。这种肿瘤被认为是恶性肉瘤巨细胞变异的同义词，经常局部复发和转移。最近，GCT-ST被描述为一种预后相对良好的独特实体，但缺乏明显的异型性和多形性，即使存在有丝分裂活动和血管侵犯。由于GCT-ST与骨巨细胞瘤在组织学和免疫组化上的相似性，目前有学者认为GCT-ST是骨巨细胞瘤的软组织类似物。一些报告记录了这些病理上的新发现，但临床病例报告中基于这些知识的影像学和手术描述非常少。作者描述的临床，放射学，形态学和组织病理学特征的GCT-ST的情况下，主要发生在大腿皮下组织的文献回顾。
Giant cell tumor of soft tissue (GCT-ST) is a rare tumor first described in 1972 by Salm and Sissons, followed shortly by Guccion and Enzinger. This tumor has been considered to be synonymous with the giant cell variant of malignant sarcoma with frequent local recurrence and metastasis. Recently GCT-ST has been described as a distinct entity of relatively benign prognosis, yet lacking marked atypia and pleomorphism, even in the presence of mitotic activity and vascular invasion. Now some authors think that GCT-ST represents the soft tissue analog of giant cell tumor of bone because of their histological and immunohistochemical similarity. Some reports documented these pathological new findings, but clinical case reports with description of imagings and surgery on the basis of these knowledge are very few. The authors describe the clinical, radiological, morphologic and histopathologial features of a case of GCT-ST occurring primarily in the subcutaneous tissue of the thigh with a review of the literature.