Detector concept for OPET - A combined PET and optical Imaging system
Detector concept for OPET - A combined PET and optical Imaging system
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DOI：
10.1109/tns.2004.829736
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发表时间：
2004-06-01
影响因子：
1.8
通讯作者：
Chatziioannou, A
中科院分区：
文献类型：
--
作者：
Prout, DL;Silverman, RW;Chatziioannou, A
一个能够探测高能伽马射线和光学波长光子的成像系统的设计正在加州大学洛杉矶分校的克分子成像研究所进行。该系统，我们称之为光学PET（OPET），将能够无创和重复成像的小动物模型在体内的PET和光学信号的存在。在这项研究中，我们描述了OPET成像系统操作背后的物理原理，并讨论了其中一个探测器模块的设计概念。此外，我们展示了一个初始的原型探测器模块的操作，同时检测和成像的湮灭辐射和单光子从不同的来源发出。这些结果表明，基于这种探测器技术的成像系统的构建是可行的。
The design of an imaging system capable of detecting both high-energy gamma-rays and optical wavelength photons is underway at the UCLA Crump Institute for Molecular Imaging. This system, which we call optical PET (OPET), will be capable of noninvasively and repeatedly imaging small animal models in vivo for the presence of PET and optical signals. In this study, we describe the physical principles behind the operation of the OPET imaging system and discuss the design concept for one of the detector modules. Additionally, we demonstrate the operation of an initial prototype detector module for simultaneous detection and imaging of annihilation radiation and single optical photons emanating from separate sources. These results indicate that the construction of an imaging system based on this detector technology is feasible.