Intramuscular hand neuroprosthesis for chronic stroke survivors
Intramuscular hand neuroprosthesis for chronic stroke survivors
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DOI：
10.1177/0888439003017002005
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发表时间：
2003-06-01
影响因子：
4.2
通讯作者：
Hart, R
中科院分区：
文献类型：
--
作者：
Chae, J;Hart, R
本研究的目的是评估经皮手神经假体系统对中风幸存者的可行性。4例慢性中风幸存者的病例报告，他们在前臂的各种肌肉中植入了经皮肌内电极，用于手的抓握和释放。经皮手神经假体能够打开痉挛性偏瘫的手，只要上肢处于休息位置，手腕和近端前臂得到支持，参与者没有试图帮助刺激，和一个人以外的参与者调制刺激。然而，当参与者试图协助刺激或完成功能任务时，由于手指屈肌张力增加，即使刺激强度增加，带开放也会显着减少。同样，电刺激的手打开后，自愿带关闭显着减少。必须开发提供实时调节张力亢进的闭环控制技术、独立于对侧肢体的控制策略以及增强近端控制的方法，以证明带式神经假体系统用于轻偏瘫患者的可行性。
The purpose of this study was to assess the feasibility of a percutaneous hand neuroprosthesis system for stroke survivors. Case reports of 4 chronic stroke survivors who were implanted with percutaneous intramuscular electrodes in various muscles of the forearm for hand grasp and release are presented. A percutaneous hand neuroprosthesis was able to open a spastic hemiparetic hand as long as the upper limb was in a resting position, the wrist and proximal forearm were supported, participants did not try to assist the stimulation, and an individual other than the participant modulated the stimulation. However, when participants tried to assist the stimulation or complete a functional task, band opening was significantly reduced due to increased finger flexor hypertonia, even with increased stimulation intensity. Similarly, electrically stimulated hand opening was significantly reduced following voluntary band closure. Techniques that provide real-time modulation of hypertonia with closed loop control, control strategies that are independent of the contralateral limb, and methods to enhance proximal control must be developed to demonstrate the feasibility of a band neuroprosthesis system for persons with hemiparesis.