Hospitalization and death associated with potentially inappropriate medication prescriptions among elderly nursing home residents
Hospitalization and death associated with potentially inappropriate medication prescriptions among elderly nursing home residents
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DOI：
10.1001/archinte.165.1.68
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发表时间：
2005-01-10
影响因子：
--
通讯作者：
Bennett, RG
中科院分区：
文献类型：
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作者：
Lau, DT;Kasper, JD;Bennett, RG
背景资料：本研究探讨了潜在的不适当的药物处方（PIRx）与住院和死亡的老年人长期入住nursing home residents.Methods：我们定义PIRx使用合并版本的啤酒标准。数据来自1996年医疗支出小组调查护理之家部分。研究样本包括3372名居民，65岁及以上，在1996年连续入住3个月或更长时间的疗养院。我们进行了多变量logistic回归分析的纵向数据，使用广义估计equations.Results：居民谁收到任何PIRx有更大的优势（优势比[OR]，1.27; P= 0.002），在接下来的一个月住院比那些没有收到PIRx。连续2个月暴露于PIRx的居民住院风险增加（OR，1.27; P= 0.004），仅在第二个月接受PIRx的居民住院风险增加（OR，1.80; P= 0.001），与未接受PIRx的居民相比。接受PIRx的居民在当月或下个月的死亡风险更高（OR，1.28; P=.01）。居民中，间歇性PlRx暴露的死亡率更高（OR，1.89; P
Background: This study examines the association of potentially inappropriate medication prescribing (PIRx) with hospitalization and death among elderly long-stay nursing home residents.Methods: We defined PIRx using the combined version of the Beers criteria. Data were from the 1996 Medical Expenditure Panel Survey Nursing Home Component. The study sample included 3372 residents, 65 years and older, who had nursing home stays of 3 consecutive months or longer in 1996. We performed multivariate logistic regression analyses of longitudinal data using generalized estimating equations.Results: Residents who received any PIRx had greater odds (odds ratio [OR], 1.27; P=.002) of being hospitalized in the following month than those receiving no PIRx. Residents with PIRx exposure for 2 consecutive months were at increased risk (OR, 1.27; P=.004) of hospitalization, as were those receiving PlRx in the second month only (OR, 1.80; P=.001), compared with those receiving' no PlRx. Residents who received PIRx were at greater risk of death (OR, 1.28; P=.01) that month or the next. Residents, vith intermittent PlRx exposures were at greater odds of death (OR, 1.89; P