The topical glucocorticoids beclomethasone dipropionate and fluticasone propionate inhibit human T‐cell allergen‐induced production of IL‐5, IL‐3 and GM‐CSF mRNA and protein

The topical glucocorticoids beclomethasone dipropionate and fluticasone propionate inhibit human T‐cell allergen‐induced production of IL‐5, IL‐3 and GM‐CSF mRNA and protein
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局部糖皮质激素二丙酸倍氯米松和丙酸氟替卡松抑制人 T 细胞过敏原诱导的 IL-5、IL-3 和 GM-CSF mRNA 和蛋白的产生

DOI:
10.1111/j.1365-2222.2001.01002.x
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发表时间:
2001
影响因子:
6.1
通讯作者:
Christopher Corrigan
Christopher Corrigan
中科院分区:
医学2区
文献类型:
--
作者:
Nick Powell;Stephen J. Till;A. B. Kay;Christopher Corrigan

文献摘要

被引文献

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T细胞产生嗜酸性粒细胞活性细胞因子(IL - 5, IL - 3, GM - CSF)被认为是哮喘发病的基础。吸入的空气过敏原可能是哮喘患者T细胞细胞因子产生的一个重要刺激。
T‐cell production of eosinophil‐active cytokines (IL‐5, IL‐3, GM‐CSF) is thought to be fundamental to asthma pathogenesis. Inhaled aeroallergens may be one important stimulus for T‐cell cytokine production in asthma.