Thalamocortical Assemblies: How Ion Channels, Single Neurons and Large-Scale Networks Organize Sleep Oscillations
Thalamocortical Assemblies: How Ion Channels, Single Neurons and Large-Scale Networks Organize Sleep Oscillations
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发表时间：
2001-12
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通讯作者：
A. Destexhe;T. Sejnowski
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作者：
A. Destexhe;T. Sejnowski
第一部分-导言1.1大脑节律性1.2对大脑节律性的早期看法1.3脑节律性的起源1.4关键神经元结构的鉴定1.5丘脑皮质组件第二部分神经元兴奋性的离子基础2.2钙依赖离子通道2.3电压依赖离子通道的马尔可夫模型第三部分丘脑中继神经元的电生理特性3.1丘脑中继神经元的爆发特性3.2丘脑中继细胞的固有振荡特性3.4丘脑中继细胞的树突状T电流第四部分丘脑网状神经元的电生理特性4.1丘脑网状细胞的反弹爆发4.2丘脑网状细胞的固有振荡4.3丘脑网状细胞的树突T电流第五部分突触相互作用的生物物理模型5.1递质释放5.2不同类型突触受体的突触传递模型5.3包括递质的细胞外扩散第六部分丘脑回路的纺锤体振荡6.1睡眠纺锤波的实验特征6.2丘脑网状核节律性的模型6.3丘脑网状核节律性模型中继网相互作用6.4为什么在体内RE核发生振荡而在体外不发生？6.5雪貂丘脑脑片纺锤波的网络模型6.6丘脑内增强反应7.1丘脑皮质系统纺锤波振荡的实验特征7.2纺锤体振荡的丘脑皮质网络模型7.3自然睡眠中纺锤波振荡的大规模同步性7.4丘脑皮质增强反应第VIII部分丘脑皮质对棘波癫痫发作的机制8.1阵发性放电发生机制的实验研究丘脑皮质系统棘波振荡的丘脑8.3模型第IX部分：睡眠振荡的生理作用？9.1丘脑输入对新皮质神经元的影响9.2自然睡眠和清醒状态下的振荡9.2睡眠振荡的可能作用9.4睡眠A离子基础B-模拟突触电流的优化算法C-互联网上的数据
PART I - INTRODUCTION 1.1 Brain rhythmicities 1.2 Early views on brain rhythmicity 1.3 Origins of brain rhythmicity 1.4 Identification of the key neuronal structures 1.5 Thalamocortical assemblies PART II - BIOPHYSICAL MODELS OF THE MEMBRANE POTENTIAL AND IONIC CURRENTS 2.1 Ionic bases of neuronal excitability 2.2 Calcium-dependent ion channels 2.3 Markov models of voltage-dependent ion channels PART III - ELECTROPHYSIOLOGICAL PROPERTIES OF THALAMIC RELAY NEURONS 3.1 The bursting properties of thalamic relay neurons 3.2 Oscillatory properties of thalamic relay cells 3.3 Intrinsic waxing-and-waning oscillations in thalamic relay cells 3.4 Dendritic T-current in thalamic relay cells PART IV - ELECTROPHYSIOLOGICAL PROPERTIES OF THALAMIC RETICULAR NEURONS 4.1 The rebound burst of thalamic reticular cells 4.2 Intrinsic oscillations in RE cells 4.3 Dendritic T-current in thalamic reticular cells PART V - BIOPHYSICAL MODELS OF SYNAPTIC INTERACTIONS 5.1 Transmitter release 5.2 Models for different types of postsynaptic receptors 5.3 Models of synaptic transmission including extracellular diffusion of transmitter PART VI - SPINDLE OSCILLATIONS IN THALAMIC CIRCUITS 6.1 Experimental characterization of sleep spindle oscillations 6.2 Models of rhythmicity in the isolated reticular nucleus 6.3 Models of rhythmicity arising from thalamic relay-reticular interactions 6.4 Why does the RE nucleus oscillate in vivo but not in vitro? 6.5 Network model of spindle oscillations in ferret thalamic slices 6.6 Intrathalamic augmenting responses PART VII - SPINDLE OSCILLATIONS IN THE THALAMOCORTICAL SYSTEM 7.1 Experimental characterization of spindle oscillations in the thalamocortical system 7.2 A thalamocortical network model of spindle oscillations 7.3 The large-scale synchrony of spindle oscillations during natural sleep 7.4 Thalamocortical augmenting responses PART VIII - THALAMOCORTICAL MECHANISMS FOR SPIKE-AND-WAVE EPILEPTIC SEIZURES 8.1 Experimental characterization of paroxysmal oscillations 8.2 Modeling the genesis of paroxysmal discharges in the thalamus 8.3 Model of spike-and-wave oscillations in the thalamocortical system PART IX - A PHYSIOLOGICAL ROLE FOR SLEEP OSCILLATIONS? 9.1 Impact of thalamic inputs on neocortical neurons 9.2 Oscillations during natural sleep and wakefulness 9.3 A possible function for sleep oscillations 9.4 A computational theory of sleep A - IONIC BASES OF THE MEMBRANE POTENTIAL B - OPTIMIZED ALGORITHMS FOR SIMULATING SYNAPTIC CURRENTS C - DATA AVAILABLE ON THE INTERNET