Correlated Movement and Bending of Nucleic Acid Structures Visualized by Multicolor Single-Molecule Spectroscopy
Correlated Movement and Bending of Nucleic Acid Structures Visualized by Multicolor Single-Molecule Spectroscopy
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DOI：
10.1002/cphc.200900109
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发表时间：
2009-07-13
期刊：
影响因子：
2.9
通讯作者：
Tinnefeld, Philip
中科院分区：
文献类型：
--
作者：
Person, Britta;Stein, Ingo H.;Tinnefeld, Philip
在彩虹的尽头…利用三重交变激光激发，研究了三向和四向︁结的结构和动力学。类固醇结合扭曲了三向连接的结构，所有分支都向更陡峭的金字塔弯曲(见图)。在四向交叉口中，三个距离的动力学被同时可视化。
At the end of the rainbow…︁The structure and dynamics of three‐ and four‐ way DNA junctions are studied using triple alternating laser excitation. Steroid binding distorts the structure of three‐way junctions with correlated bending of all branches towards a steeper pyramid (see picture). In four‐way junctions, the dynamics of three distances are visualized simultaneously.