COVALENT ATTACHMENT OF CHELATING GROUPS TO MACROMOLECULES
COVALENT ATTACHMENT OF CHELATING GROUPS TO MACROMOLECULES
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DOI:
10.1016/s0006-291x(77)80018-1
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发表时间:
1977-01-01
影响因子:
3.1
通讯作者:
TUCKER, KL
中科院分区:
文献类型:
--
作者:
KREJCAREK, GE;TUCKER, KL
A simple procedure is described for covalently coupling diethylenetriaminepentaacetic acid (DTPA) to proteins. The technique creates hexadentate chelating sites for metal ions on proteins. A variety of metals with useful physical properties can be specifically bound to DTPA modified macromolecules. These metal-macromolecule complexes can be useful as probes in biological systems.