Induction of gram-negative bacterial growth by neurochemical containing banana (Musa x paradisiaca) extracts.
Induction of gram-negative bacterial growth by neurochemical containing banana (Musa x paradisiaca) extracts.
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通过含有香蕉（Musa x paradisiaca）提取物的神经化学物质诱导革兰氏阴性细菌生长。
DOI：
10.1111/j.1574-6968.1997.tb12651.x
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发表时间：
1997
影响因子：
2.1
通讯作者：
Lyte,M
中科院分区：
文献类型：
--
作者：
Lyte,M
香蕉含有大量的神经化学物质。从不同成熟阶段的香蕉果皮和果肉中提取提取物，并评价其对非病原菌和病原菌生长的调节作用。果皮和果肉的提取物对革兰氏阴性杆菌、志贺氏菌、阴沟肠杆菌和鼠伤寒沙门氏菌以及两种非致病菌E的生长有促进作用，程度较小。秋水仙素，与去甲肾上腺素和多巴胺的含量直接相关，而与5-羟色胺无关。革兰氏阳性菌的生长不受任何提取物的影响。添加去甲肾上腺素或多巴胺的载体和牙髓培养物可产生与果皮培养相当的生长。对提取物的全有机分析进一步表明，果皮和果肉对细菌生长的不同影响不是基于营养，而是由于去甲肾上腺素和多巴胺。这些结果表明，食品中含有的神经化学物质可能通过直接的神经化学-细菌相互作用影响病原菌和本地细菌的生长。
Bananas contain large quantities of neurochemicals. Extracts from the peel and pulp of bananas in increasing stages of ripening were prepared and evaluated for their ability to modulate the growth of non-pathogenic and pathogenic bacteria. Extracts from the peel, and to a much lesser degree the pulp, increased the growth of Gram-negative bacterial strainsEscherichia coliO157:H7,Shigella flexneri,Enterobacter cloacaeandSalmonella typhimurium, as well as two non-pathogenicE. colistrains, in direct relation to the content of norepinephrine and dopamine, but not serotonin. The growth of Gram-positive bacteria was not altered by any of the extracts. Supplementation of vehicle and pulp cultures with norepinephrine or dopamine yielded growth equivalent to peel cultures. Total organic analysis of extracts further demonstrated that the differential effects of peel and pulp on bacterial growth was not nutritionally based, but due to norepinephrine and dopamine. These results suggest that neurochemicals contained within foodstuffs may influence the growth of pathogenic and indigenous bacteria through direct neurochemical-bacterial interactions.