Cognitive function and number of teeth in a community-dwelling elderly population without dementia
Cognitive function and number of teeth in a community-dwelling elderly population without dementia
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DOI：
10.1111/j.1365-2842.2009.01998.x
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发表时间：
2009-11-01
影响因子：
2.9
通讯作者：
Takehara, T.
中科院分区：
文献类型：
--
作者：
Takata, Y.;Ansai, T.;Takehara, T.
尽管在患有痴呆症的老年人群中，健康或腐烂的牙齿的数量与认知功能有关，但在没有痴呆症的老年人群中，这种联系却知之甚少。我们在日本福冈县60岁(n=270；120男性和150女性)和65岁(n=123；57男性和66女性)人群中评估了这种关系，并对混杂因素进行了调整。所有受试者都进行了牙科检查，同时还进行了简易智力状态检查(MMSE)以评估认知功能。在393名受试者中，MMSE平均得分为27中心点9+/-1中心点9,391名受试者得分在24或以上。健牙和龋齿的平均数分别为12个中心点0+/-6个中心点3和0个中心点5+/-1个中心点2。通过调整性别、年龄、教育水平、婚姻状况、吸烟、饮酒、工作状态、收缩压和血糖的多元回归分析，发现在所有受试者和男性中，健康牙齿和腐烂牙齿的数量与MMSE之间存在关联，而在女性中没有关联。Logistic回归分析还发现，MMSE与健齿数量之间也存在关联。总而言之，在日本老年人群中，在调整了各种混杂因素后，发现正常范围的认知功能与健全牙齿和腐烂牙齿的数量之间存在关联。
P>Although the number of sound or decayed teeth has been reported to be associated with cognitive function in elderly populations with dementia, little is known about this association in elderly populations without dementia. We evaluated this relationship, with adjustment for confounding factors, in Japanese populations of 60-year-old (n = 270; 120 males and 150 females) and 65-year-old (n = 123; 57 males and 66 females) individuals residing in Fukuoka Prefecture of Japan. Dental examinations were performed in all subjects, along with the Mini-mental state examination (MMSE) for assessing cognitive function. Among the total of 393 subjects, the mean MMSE score was 27 center dot 9 +/- 1 center dot 9, and 391 subjects scored 24 or higher. The mean numbers of sound and decayed teeth were 12 center dot 0 +/- 6 center dot 3 and 0 center dot 5 +/- 1 center dot 2, respectively. Associations were found between the numbers of sound and decayed teeth and MMSE in total subjects and males, but not in females, by multiple regression analysis adjusted for gender, age, level of education, marital status, smoking, alcohol drinking, working status, systolic blood pressure and blood glucose. An association was also found between MMSE and the number of sound teeth in a logistic regression analysis. In conclusion, associations were found between normal-range cognitive function and the numbers of sound and decayed teeth, after adjustment for various confounding factors, in an elderly Japanese population.