Contributors to osteoporosis development
Contributors to osteoporosis development
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DOI：
10.1007/s00198-003-1454-8
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发表时间：
2003-10-01
影响因子：
4
通讯作者：
Carter, DR
中科院分区：
文献类型：
--
作者：
Hernandez, CJ;Beaupré, GS;Carter, DR
决定绝经后妇女骨密度(BMD)的因素包括她在骨骼成熟时的质量(峰值BMD)、绝经和她随着年龄的增长所经历的损失速度。了解这些因素的相对影响可能有助于确定重要的预防性治疗，并提供新的方法来确定处于骨质疏松症风险中的妇女。在这项分析中，我们利用骨重建过程的计算机模型来预测峰值骨密度、绝经和年龄相关性骨丢失对骨质疏松症发展的相对影响。骨质疏松症(定义为BMD)的发病延迟
Factors that determine a post-menopausal woman's bone mineral density (BMD) include her mass at the time of skeletal maturity (peak BMD), menopause and the rate of loss she experiences as she ages. Understanding the relative influence of each of these factors may help identify important preventive treatments and provide new ways to identify women at risk for osteoporosis. In this analysis we utilize a computer model of the bone remodeling process to predict the relative influences of peak BMD, menopause and age-related bone loss on the development of osteoporosis. The delay in the onset of osteoporosis (defined as BMD