INTERACTIONS OF MELANIN WITH METAL-IONS - ELECTRON-SPIN RESONANCE EVIDENCE FOR CHELATE COMPLEXES OF METAL-IONS WITH FREE-RADICALS
INTERACTIONS OF MELANIN WITH METAL-IONS - ELECTRON-SPIN RESONANCE EVIDENCE FOR CHELATE COMPLEXES OF METAL-IONS WITH FREE-RADICALS
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DOI：
10.1021/ja00480a044
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发表时间：
1978-01-01
影响因子：
15
通讯作者：
SEALY, RC
中科院分区：
文献类型：
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作者：
FELIX, CC;HYDE, JS;SEALY, RC
ESR实验表明，二-和三正金属离子结合到黑色素聚合物内的o-半醌自由基中心，产生螯合物。结合通常伴随着总自由基浓度的大幅增加，这被认为是通过金属离子引起的在歧化平衡中的移动而产生的。所观察到的效果可能是一般的自由基与螯合能力，并可能会发现在其他生物系统中的复合ESR信号的分离和识别使用。
ESR experiments reveal that di- and tripositive metal ions bind to o-semiquinone radical centers within melanin polymers to yield chelate complexes. The binding is often accompanied by large increases in total radical concentration, which are considered to arise via metal ion induced shifts in a comproportionation equilibrium. The effects observed are likely to be general for radicals with chelating ability, and may find use in the separation and identification of composite ESR signals in other biological systems.