Translation and Adaptation of the Genetic Counselling Outcome Scale (GCOS-24) for Use in Denmark
Translation and Adaptation of the Genetic Counselling Outcome Scale (GCOS-24) for Use in Denmark
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DOI：
10.1007/s10897-017-0086-7
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发表时间：
2017-10-01
影响因子：
1.9
通讯作者：
McAllister, Marion
中科院分区：
文献类型：
--
作者：
Diness, Birgitte Rode;Overbeck, Gritt;McAllister, Marion
临床遗传学的结果测量具有挑战性。需要强有力的结果措施，以提供证据，支持遗传咨询服务的发展。遗传咨询结果量表（GCOS-24）是一种患者报告的结果测量（PROM），用英语开发，并在英国NHS的临床遗传学患者中进行验证。本研究报告了GCOS-24在丹麦的翻译和改编情况。在一个专家委员会的监督下，对GCOS-24进行了翻译和回译。第一个版本的反馈收集遗传咨询患者的定性访谈，重点是使用说明，响应选项和特定的项目被认为是语义上的困难。在进一步调整后，将改编和翻译的版本施用于第二个患者样本，使用描述性统计分析反应。进行了18次访谈，并导致项目措辞的调整。61例患者完成了最终版本GCOS-24 dk。内部一致性良好（Cronbach's alpha =0.79），缺失响应的数量可接受，未观察到下限或上限效应。GCOS-24已成功地翻译和改编，供丹麦使用。该研究证实了当地适应患者报告的结果措施的可行性，并强调适应的重要性，即使在非常相似的人群和医疗保健系统。
Outcome measurement in clinical genetics is challenging. Robust outcome measures are needed to provide evidence to support service development within genetic counseling. The Genetic Counselling Outcome Scale (GCOS-24), a Patient Reported Outcome Measure (PROM), was developed in English and validated with clinical genetics patients in the British NHS. This study reports the translation and adaptation of the GCOS-24 for use in Denmark. GCOS-24 was translated and back translated, supervised by an expert committee. Feedback on the first version was collected from genetic counseling patients in qualitative interviews focusing on instructions for use, response options and specific items considered semantically difficult. After further adjustment the adapted and translated version was administered to a second sample of patients, with responses analyzed using descriptive statistics. Eighteen interviews were conducted, and led to adjustment of item wording. Sixty-one patients completed the final version GCOS-24dk. Internal consistency is good (Cronbach's alpha =0.79), with an acceptable number of missing responses and no floor or ceiling effect observed. GCOS-24 has been successfully translated and adapted for use in a Danish setting. The study confirms the feasibility of local adaptation of patient reported outcome measures and stresses the importance of adaptation, even across quite similar populations and health care systems.