Reasons for Benzodiazepine Use Among Persons Seeking Opioid Detoxification
Reasons for Benzodiazepine Use Among Persons Seeking Opioid Detoxification
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DOI：
10.1016/j.jsat.2016.06.008
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发表时间：
2016-09-01
影响因子：
3.9
通讯作者：
Bailey, Genie L.
中科院分区：
文献类型：
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作者：
Stein, Michael D.;Kanabar, Mitika;Bailey, Genie L.
背景：在过去的十年里，接受成瘾治疗计划的患者报告说，阿片类药物和苯二氮卓类药物(BZD)的同时使用率增加。这种药物组合使个人面临意外过量的高风险。在寻求治疗阿片类药物使用障碍的患者中使用BZD的原因知之甚少。方法：我们连续调查了开始住院阿片类药物戒毒的438人中的176人，其中176人报告在过去30天内使用BZD和/或毒理学阳性。结果：40%的被调查者在入院前一个月使用BZD，其中25%的人符合BZD依赖标准(DSM IV)。BZD吸毒者平均年龄为32.0岁，其中63.6%为男性，85.2%吸食海洛因，并报告在过去一个月中平均使用BZD 13.3(+/-11.2)天。阿普唑仑(Xanax)是最常用的BZD(52%)，最常见的来源是街头购买(48%)。据报道，使用BZD的最常见原因是“控制焦虑”(42.6%)，其次是“获得或增强快感”(27.7%)，“帮助睡眠”(11.4%)，以及“减少阿片类药物的戒断”(10.2%)。使用BZD的最常见原因是显著相关(p
Background: Over the past decade, patients admitted to addiction treatment programs have reported increasing rates of concurrent opioid and benzodiazepine (BZD) use. This drug combination places individuals at high risk for accidental overdose. Little is known about reasons for BZD use among individuals seeking treatment for opioid use disorders.Methods: We surveyed consecutive persons initiating inpatient opioid detoxification and identified 176 out of 438 who reported BZD use in the past 30 days and/or had a positive toxicology.Results: Forty percent of persons surveyed used a BZD in the month prior to admission, and 25% of these met criteria for BZD dependence (DSM IV). BZD users averaged 32.0 years of age, 63.6% were male, 85.2% used heroin, and reported, on average, 13.3 ( +/-11.2) days of BZD use during the past month. Alprazolam (Xanax) was the most commonly used BZD (52%), and buying it on the street the most common source (48%). The most commonly reported reason for BZD use was 'to manage anxiety' (42.6%), followed by 'to get or enhance a high' (27.7%), 'to help with sleep' (11.4%), and 'to decrease opioid withdrawal' (10.2%). The most common reason for BZD use was significantly associated (p