Expression of a novel mammalian epidermal growth factor-related gene during mouse neural development
Expression of a novel mammalian epidermal growth factor-related gene during mouse neural development
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DOI：
10.1016/s0925-4773(00)00586-4
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发表时间：
2001-04-01
影响因子：
2.6
通讯作者：
Greenfield, A
中科院分区：
文献类型：
--
作者：
Grimmond, S;Larder, R;Greenfield, A
我们最近报道了一种新的EGF相关基因Scube1（信号肽CUB结构域EGF相关，基因1）的初步特征，该基因在发育中的性腺，神经系统，体节，表面外胚层和肢芽的小鼠显着表达。在这里，我们描述了一个密切相关的基因，Scube 2（也称为Cegp 1），它映射到小鼠7号染色体的远端区域的表达模式。Scube2的转录仅限于胚胎神经外胚层，但也可在成人心脏、肺和睾丸中检测到。(C)2001爱思唯尔科学爱尔兰有限公司保留所有权利。
We have recently reported the preliminary characterisation of a novel EGF-related gene, Scube1 (signal peptide-CUB domain-EGF-related, gene 1), that is expressed prominently in the developing gonad, nervous system, somites, surface ectoderm and limb buds of the mouse. Here we describe the expression pattern of a closely related gene, Scube2 (also known as Cegp1), which maps to the distal region of mouse chromosome 7. Scube2 transcription is restricted to the embryonic neurectoderm but is also detectable in the adult heart, lung and testis. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.