Accelerator or Brake: Immune Regulators in Malaria.
Accelerator or Brake: Immune Regulators in Malaria.
复制标题
加速器还是刹车:疟疾中的免疫调节器
DOI:
10.3389/fcimb.2020.610121
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发表时间:
2020
影响因子:
5.7
通讯作者:
Yu X
中科院分区:
文献类型:
--
作者:
Cai C;Hu Z;Yu X
Malaria is a life-threatening infectious disease, affecting over 250 million individuals worldwide each year, eradicating malaria has been one of the greatest challenges to public health for a century. Growing resistance to anti-parasitic therapies and lack of effective vaccines are major contributing factors in controlling this disease. However, the incomplete understanding of parasite interactions with host anti-malaria immunity hinders vaccine development efforts to date. Recent studies have been unveiling the complexity of immune responses and regulators against Plasmodium infection. Here, we summarize our current understanding of host immune responses against Plasmodium-derived components infection and mainly focus on the various regulatory mechanisms mediated by recent identified immune regulators orchestrating anti-malaria immunity.
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影响因子:
30.5
作者:
Blackburn, Shawn D.;Shin, Haina;Haining, W. Nicholas;Zou, Tao;Workman, Creg J.;Polley, Antonio;Betts, Michael R.;Freeman, Gordon J.;Vignali, Dario A. A.;Wherry, E. John
通讯作者:
Wherry, E. John
DOI:
10.4049/jimmunol.1500368
发表时间:
2016-08-15
期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
--
作者:
Barnett BE;Staupe RP;Odorizzi PM;Palko O;Tomov VT;Mahan AE;Gunn B;Chen D;Paley MA;Alter G;Reiner SL;Lauer GM;Teijaro JR;Wherry EJ
通讯作者:
Wherry EJ
影响因子:
4
作者:
Ablack, Jailal N. G.;Metz, Patrick J.;Ginsberg, Mark H.
通讯作者:
Ginsberg, Mark H.
影响因子:
4.8
作者:
Behrens, Maik;Bartelt, Juliane;Meyerhof, Wolfgang
通讯作者:
Meyerhof, Wolfgang
影响因子:
3
作者:
Baker, Virginia S.;Imade, Godwin E.;Molta, Norman B.;Tawde, Pallavi;Pam, Sunday D.;Obadofin, Michael O.;Sagay, Soloman A.;Egah, Daniel Z.;Iya, Daniel;Afolabi, Bangmboye B.;Baker, Murray;Ford, Karen;Ford, Robert;Roux, Kenneth H.;Keller, Thomas Cs
通讯作者:
Keller, Thomas Cs