Safety and Effectiveness of Endovenous Laser Ablation Combined With Ligation for Severe Saphenous Varicose Veins in Japanese Patients
Safety and Effectiveness of Endovenous Laser Ablation Combined With Ligation for Severe Saphenous Varicose Veins in Japanese Patients
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DOI：
10.1536/ihj.15-282
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发表时间：
2016-01-01
影响因子：
1.5
通讯作者：
Abo, Yoshihisa
中科院分区：
文献类型：
--
作者：
Izumi, Masafumi;Ikeda, Yuichi;Abo, Yoshihisa
静脉腔内激光消融术（EVLA）是治疗下肢隐静脉曲张的一种相对较新的治疗方法，其侵入性低于传统的结扎剥脱手术。在这项研究中，我们评价了EVLA联合结扎治疗CEAP分级≥ C-4级的严重隐静脉曲张的安全性和有效性。我们在2005年7月至2007年12月期间使用1320 nm Nd：YAG激光治疗了119名日本患者（141条肢体）。在整个随访期间（2.5年），治疗静脉的闭塞率为100%。与这一发现一致，所有患者均表现出皮肤病变改善（即皮肤色素沉着和溃疡）。没有观察到严重并发症，包括深静脉血栓形成（DVT）和神经损伤。问卷调查的合理应答率（66.4%）表明，EVLA后最初观察到的主观症状和轻微并发症（如轻度疼痛、麻木、硬结和局部潮热）在随访期结束时显著改善。此外，患者满意度也很高。因此，EVLA联合结扎是治疗日本患者严重隐静脉曲张的安全有效的策略。
Endovenous laser ablation (EVLA), which is a relatively new therapeutic option for saphenous varicose veins of the legs, is less invasive than conventional stripping surgery with ligation. In this study, we evaluated the safety and effectiveness of EVLA combined with ligation for severe saphenous varicose veins that were graded as >= C-4 by the CEAP classification. We treated 119 Japanese patients (141 limbs) between July 2005 and December 2007 utilising a 1320-nm Nd:YAG laser. The obliteration rate of the treated veins was found to be 100% over the entire follow-up period (2.5 years). Consistent with this finding, all of the patients exhibited improved skin lesions (ie, skin pigmentation and ulceration). No major complications, including deep vein thrombosis (DVT) and nerve injury, were observed. A questionnaire survey with a reasonable response rate (66.4%) demonstrated that subjective symptoms and minor complications that were initially observed after EVLA, such as mild pain, numbness, indurations, and localized hot flashes, were remarkably improved by the end of the follow-up period. Furthermore, high levels of patient satisfaction were noted. Thus, EVLA combined with ligation constituted a safe and effective strategy for treating severe saphenous varicose veins in Japanese patients.