A CASE-CONTROL STUDY OF BILIARY-TRACT CANCER IN NIIGATA-PREFECTURE, JAPAN

A CASE-CONTROL STUDY OF BILIARY-TRACT CANCER IN NIIGATA-PREFECTURE, JAPAN
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DOI:
10.1111/j.1349-7006.1989.tb01629.x
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发表时间:
1989-10-01
期刊:
JAPANESE JOURNAL OF CANCER RESEARCH
影响因子:
--
通讯作者:
KATO, I
KATO, I
中科院分区:
其他
文献类型:
--
作者:
KATO, K;AKAI, S;KATO, I

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在日本胆道癌死亡率最高的新泻县进行了胆道癌病例对照研究。109例胆囊癌患者和84例胆管癌患者,对照组为386例性别和年龄相匹配的社区对照。对于胆囊癌来说,既往有胆道疾病史、有胆石症家族史和喜欢吃油腻的食物是高风险因素。摄入鱼类、蛋类、肉类等动物蛋白和脂肪,摄入蔬菜和水果,吃零食是患胆囊癌的低危险因素。胆管癌的高危因素有胆道疾病史、脑血管意外家族史、体质瘦弱、食物摄入少等,有心脏病家族史、肥胖、摄入酒精、动物蛋白和脂肪、频繁摄入蔬菜水果等为低危因素。
A case-control study of biliary tract cancer was conducted in Niigata prefecture where the mortality of the cancer is the highest in Japan. The cases were 109 patients with gallbladder cancer and 84 with bile duct cancer, and the controls were 386 sex- and age-matched neighborhood controls. For gallbladder cancer, a past history of biliary tract disease, a positive family history of cholelithiasis and a taste of oily foods were high risk factors. Intakes of animal proteins and fats such as fish, eggs, meat, etc., ingestion of vegetables and fruits, and taking snacks were low risk factors for gallbladder cnacer. For bile duct cancer, a past history of biliary tract disease, a family history of cerebral vascular accident, a thin constitution and taking a small amount of foods were high risk factors, and a family history of heart disease, obesity, intakes of alcohol, animal proteins and fats, or frequent intakes of vegetables and fruits were low risk factors.