Effects of modified electroconvulsive therapy on the electroencephalogram of schizophrenia patients.
Effects of modified electroconvulsive therapy on the electroencephalogram of schizophrenia patients.
复制标题
改良电休克疗法对精神分裂症患者脑电图的影响
DOI：
10.1186/s40064-016-2747-7
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发表时间：
2016
期刊：
影响因子：
--
通讯作者：
Zhang H
中科院分区：
文献类型：
--
作者：
Zhao L;Jiang Y;Zhang H
本研究旨在探讨改良电惊厥疗法(MECT)对精神分裂症患者脑电的影响。研究对象为26例接受无抽搐电休克治疗的精神分裂症患者。EEG记录于MECT前30min开始，第2天终止。选择无伪影图像进行δ，θ，α-1、α-2和β条带分析。测定并比较各频段的波能量、同一导联不同频段的波群指数、同一频段不同导联的波群指数、癫痫放电时间、静息时间、达到稳定脑电的时间。额颞区α波减少，θ波增加。θ波指数增加。静息状态后，脑电波首先出现在额区。两组波群恢复正常的时间差异有统计学意义(P=0.05)。结论电疗后同导联θ波增多，能量也升高，额颞区α波减少，出现一过性脑功能减退。在静息状态下，脑电波主要出现在额叶区域，MECT后脑波恢复正常的时间随时间缩短。
BackgroundThis study aimed to investigate the modified electroconvulsive therapy (MECT) on the electroencephalogram (EEG) of schizophrenia patients. A total of 26 schizophrenia patients who received MECT were recruited. EEG recording was initiated at 30 min before 1st and 6th MECT and terminated on the 2nd day. Images without artifacts were selected for the analysis of δ, θ, α1, α2 and β bands. The wave energy at each frequency, index of waves at different bands from the same lead, index of waves at the same band from different leads, time of epileptic discharge, time of resting state, and time to the stable EEG were determined and compared.ResultsThe energy of slow waves increased. α waves reduced, but θ waves increased in the frontotemporal area. The index of θ waves increased. After resting state, brainwaves first occurred in the frontal area. Significant difference was observed in the time to waves returning to normal (P= 0.05).ConclusionsAfter MECT, the θ waves in the same lead increases, and its energy also elevates; α wave in the frontotemporal area reduces; there is transient reduction in cerebral function during MECT. After electric resting state, brainwaves mainly occur in the frontal area, and the time to brainwaves returning to normal reduces over time after MECT.