Distribution of syringomyelia along the entire spinal cord in clinically affected Cavalier King Charles Spaniels
Distribution of syringomyelia along the entire spinal cord in clinically affected Cavalier King Charles Spaniels
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DOI：
10.1016/j.tvjl.2010.12.002
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发表时间：
2011-12-01
影响因子：
2.2
通讯作者：
Volk, Holger A.
中科院分区：
文献类型：
--
作者：
Loderstedt, Shenja;Benigni, Livia;Volk, Holger A.
chiaria -like malformation (CM) and syringomyelia （SM）是Cavalier King Charles Spaniel （CKCS）中一种重要的疾病复合体，但在兽医学上缺乏SM沿脊髓的解剖分布资料。本研究的目的是确定CM/SM临床影响的CKCS中SM的解剖分布。对49只狗的大脑和整个脊髓进行了磁共振成像（MRI），并对不同形态学参数进行了比较。C1-C4区和脊髓的其他部位均可见脊髓鸣管形成。脊髓的任何部位均可出现最大背腹侧灌管大小，且总灌管大小与年龄呈正相关。76%的CKCS伴有颅颈腔炎同时也有影响更多尾侧脊髓区域的腔炎。在大多数犬中，局限于颈椎区域的MRI可能低估了SM的程度和疾病过程的严重性。(C) 2010 Elsevier Ltd.版权所有。
Chiari-like malformation (CM) and syringomyelia (SM) is an important disease complex in the Cavalier King Charles Spaniel (CKCS) but data about the anatomical distribution of SM along the spinal cord are lacking in veterinary medicine. The objective of this study was to define the anatomic distribution of SM in CKCS clinically affected by CM/SM. Magnetic resonance imaging (MRI) of the brain and the entire spinal cord of 49 dogs was performed and different morphological parameters compared.Syrinx formation was present in the C1-C4 region and in other parts of the spinal cord. The maximal dorsoventral syrinx size can occur in any region of the spinal cord and the total syrinx size was positively correlated with age. Seventy-six per cent of CKCS with a cranial cervical syrinx also have a syrinx affecting more caudal spinal cord regions. MRI restricted to the cervical region may underestimate the extent of SM and the severity of the disease process in the majority of dogs. (C) 2010 Elsevier Ltd. All rights reserved.