C2PA, a new protein expressed during mouse spermatogenesis
C2PA, a new protein expressed during mouse spermatogenesis
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C2PA，一种在小鼠精子发生过程中表达的新蛋白质
DOI：
10.1016/s0014-5793(00)01942-6
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发表时间：
2000
期刊：
影响因子：
3.5
通讯作者：
M. Rio
中科院分区：
文献类型：
--
作者：
J. Linares;C. Wendling;C. Tomasetto;M. Rio
C2PA是一种含有C2膜结合域、PDZ蛋白/蛋白相互作用域和ATP/GTP结合域的新型蛋白。C2PA在胚胎发生过程中从性交后8.5天（dpc）开始表达直到出生。出生后，C2PA主要在产后和成年睾丸中表达。在精子发生过程中，在精母细胞中特异性观察到C2PA转录本，而精原细胞和精母细胞是阴性的。综上所述，这些结果表明C2PA可能参与了精子发生过程中的细胞信号通路。
C2PA is a novel protein that contains a C2 membrane binding domain, a PDZ protein/protein interaction domain, and an ATP/GTP binding domain. C2PA is expressed during embryogenesis from 8.5 days post-coitum (dpc) until birth. After birth, C2PA expression is mainly observed in the post-natal and adult testis. During spermatogenesis, C2PA transcripts are specifically observed in the spermatocytes, whereas spermatogonia and spermatids are negative. Taken together, these results suggest that C2PA might be involved in cell signaling pathways occurring during spermatogenesis.
钙依赖性脂质结合蛋白形成膜结构域：来自 C2 基序的见解。
DOI：
10.1016/s0167-4889(98)00146-3
发表时间：
1998
期刊：
Biochimica et biophysica acta
影响因子：
--
作者：
Hinderliter,AK;Almeida,PF;Biltonen,RL;Creutz,CE
通讯作者：
Creutz,CE