The Heredity of Behavior Disorders in Adults and Children
The Heredity of Behavior Disorders in Adults and Children
复制标题
成人和儿童行为障碍的遗传
DOI：
10.1007/978-1-4684-5071-2
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发表时间：
1986
影响因子：
7.6
通讯作者：
D. Pauls
中科院分区：
文献类型：
--
作者：
S. G. Vandenberg;S. Singer;D. Pauls
目前的发病率趋势表明，到二十一世纪初，精神疾病可能成为许多发达国家公共卫生中最紧迫的问题。正如Vandenberg、Singer和Pauls所证明的那样，主要精神疾病的主要可识别病因是遗传;如果要在预防和治疗这些疾病方面取得进展，可能必须来自对其遗传的更好理解。人们观察到，情绪障碍的发病率不断增加，主要是重性抑郁症，但也有躁狂抑郁症，自（大约）1940年以来，每个年龄组的人都出现得更早、更频繁。由于重性抑郁症是一种复发性疾病，其发作频率随着年龄的增长而增加，因此可以预期，随着这些人进入中年和老年，观察到的抑郁症的数量会急剧增加。根据出生队列，自杀率也大幅上升。从1935年左右出生的人开始，15至19岁之间的自杀率从最早到最近的出生队列增加了10倍以上。目前尚不清楚的是，随着年龄的增长，自杀率是否会出现补偿性下降，因为可能自杀的人会更早地自杀，或者这是否预示着自杀的普遍增加，与情绪障碍的增加相当，也许是它们的一个功能。"
Current trends in morbidity suggest that by the beginning of the twen ty-first century, psychiatric illness may become the most pressing problem in public health in many of the advanced countries. As ably demonstrated by Vandenberg, Singer, and Pauls, the principal identifia ble etiology of the major psychiatric disorders is heredity; if progress is to be made in prevention and treatment of these disorders, it may have to come from improved understanding of their inheritance. A relentless increase has been observed in the frequency of mood disorders, primarily major depression but also manic-depressive ill ness, appearing earlier and more frequently in each age cohort born since (approximately) 1940. Because major depression is a recurrent disorder, whose episodes increase in frequency with age, the number of observed depressions can be expected to increase dramatically as these people reach middle and old age. The rate of suicide has also increased enormously, according to birth cohort. Starting with people born around 1935, the rate of suicide between 15 and 19 years of age has increased more than 10 times from the earliest to the most recent birth cohorts. What is not clear is if there will be a compensatory reduction in suicide rate as this cohort ages, because people likely to commit suicide will have done so earlier, or if this presages a general increase in suicide, comparable to the increase in mood disorders and perhaps a function of them."
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重度抑郁症中的食欲障碍和过度内疚。
影响因子：
--
作者：
Leckman,JF;Caruso,KA;Prusoff,BA;Weissman,MM;Merikangas,KR;Pauls,DL
通讯作者：
Pauls,DL
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DOI：
10.1176/ajp.141.7.892
发表时间：
1984
期刊：
The American journal of psychiatry
影响因子：
--
作者：
Weissman,MM;Prusoff,BA;Merikangas,KR
通讯作者：
Merikangas,KR
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影响因子：
--
作者：
Kidd,KK;Prusoff,BA;Cohen,DJ
通讯作者：
Cohen,DJ
瑞典被收养者有轻微犯罪倾向。
影响因子：
--
作者：
Sigvardsson,S;Cloninger,CR;Bohman,M;vonKnorring,AL
通讯作者：
vonKnorring,AL
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影响因子：
1.8
作者：
Rao,DC;Morton,NE;Gottesman,II;Lew,R
通讯作者：
Lew,R