Prevalence and factors associated with the presence of nonalcoholic fatty liver disease in an adult population in Spain
Prevalence and factors associated with the presence of nonalcoholic fatty liver disease in an adult population in Spain
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DOI：
10.1097/meg.0b013e32832fcdf0
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发表时间：
2010-01-01
影响因子：
2.1
通讯作者：
Maite Aizpurua, Miren
中科院分区：
文献类型：
--
作者：
Caballeria, Llorenc;Pera, Guillem;Maite Aizpurua, Miren
背景/目的西班牙非酒精性脂肪性肝病（NAFLD）的患病率尚不清楚。检测NAFLD患者的目的是确定相关因素，防止其演变为更严重的形式。本研究的目的是确定NAFLD的患病率和相关因素。方法本研究为多中心、横断面、人群研究。从西班牙巴塞罗那省25个初级保健中心随机抽取15至85岁的个体。回顾了临床病史，并进行了记忆、体格检查、血液分析和肝脏超声检查。男性酒精摄入量大于30克/天，女性酒精摄入量大于20克/天或患有已知肝脏疾病的个体被排除在外。结果共纳入766例患者，平均年龄53 +/- 14岁（17-83岁，男性占42.2%）。198例患者经超声诊断为NAFLD（患病率25.8%，男性33.4%，女性20.3%）
Background/aims The prevalence of nonalcoholic fatty liver disease (NAFLD) is unknown in Spain. The purpose of detecting NAFLD patients is to determine the associated factors and prevent its evolution to more severe forms. The aim of this study is to determine the prevalence and factors associated with NAFLD.Methods This is a multicentre, cross-sectional, populational study. Individuals between 15 and 85 years of age were randomly selected from 25 primary healthcare centres in the province of Barcelona, Spain. Clinical histories were reviewed, and anamnesis, physical examination, blood analysis and hepatic echography were performed. Individuals with an alcohol intake greater than 30 g/day in men and greater than 20 g/day in women or with known liver disease were excluded.Results Seven hundred and sixty-six individuals with a mean age of 53 +/- 14 years (range 17-83, 42.2% men) were included in the study. One hundred and ninety-eight individuals presented NAFLD with echographic criteria (prevalence 25.8, 33.4% men and 20.3% women P