REFLEXES TO SACRAL PARASYMPATHETIC NEURONES CONCERNED WITH MICTURITION IN CAT
REFLEXES TO SACRAL PARASYMPATHETIC NEURONES CONCERNED WITH MICTURITION IN CAT
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DOI：
10.1113/jphysiol.1969.sp008683
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发表时间：
1969-01-01
影响因子：
5.5
通讯作者：
RYALL, RW
中科院分区：
文献类型：
--
作者：
DEGROAT, WC;RYALL, RW
1. 通过电生理技术研究了失脑、氯氯蔗糖麻醉和慢性脊髓猫对骶部副交感神经元的反射。慢性脊髓横断前后均有盆腔神经和骶椎体传入神经纤维的兴奋性反射，但潜伏期明显不同。结论是，脊髓完好时观察到的长潜伏期反射涉及到脑干的长回路反射。当脊髓完好时，慢性脊髓猫的弱、短潜伏期反射从未被观察到，这可能是由于脊髓连接重组所致。短潜伏期反射在正常排尿中可能不重要。刺激骨盆或骶骨躯体神经的传入纤维产生短潜伏期抑制性突触后电位（IPSPs）和抑制副交感神经元的放电。这种抑制是由于脊髓反射。盆腔神经丛有局部反射。这可能是一种胆碱能轴突反射，但不排除它是涉及膀胱壁感觉神经元的局部胆碱能反射的可能性。
1. Reflexes to sacral parasympathetic neurones were studied by electrophysiological techniques in decerebrate, in chloralose‐anaesthetized, and in chronic spinal cats.2. Excitatory reflexes from pelvic nerve and sacral somatic afferent nerve fibres were present before and after chronic transection of the spinal cord, but the latencies differed markedly. It was concluded that the long‐latency reflexes observed when the spinal cord was intact involved long‐loop reflexes to the brain‐stem. The weak, short‐latency reflexes in the chronic spinal cat were never observed when the spinal cord was intact and could be due to reorganized spinal connexions. The short‐latency reflexes are probably unimportant in normal micturition.3. Stimulation of afferent fibres in the pelvic or sacral somatic nerves produced short‐latency inhibitory post‐synaptic potentials (IPSPs) and inhibition of discharges in parasympathetic neurones. This inhibition was due to a spinal reflex.4. A local reflex was demonstrated in the pelvic plexus. This was probably a cholinergic axon reflex, but the remote possibility that it was a local cholinergic reflex involving sensory neurones in the bladder wall has not been excluded.