A novel porous Ti6Al4V: Characterization and cell attachment
A novel porous Ti6Al4V: Characterization and cell attachment
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DOI：
10.1002/jbm.a.30278
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发表时间：
2005-05-01
影响因子：
4.9
通讯作者：
de Groot, K
中科院分区：
文献类型：
--
作者：
Li, JP;Li, SH;de Groot, K
首次采用“聚合物海绵复制法”制备了高孔隙度的高强度Ti6 Al 4V。对用由Ti6 Al 4V粉末和粘合剂制备的Ti6 Al 4V浆料浸渍的聚合物海绵进行干燥和热解以除去聚合物海绵和粘合剂。在高温和高真空下烧结后，制备出多孔Ti6 A14 V。对所得多孔Ti6 A14 V进行了光学显微镜观察、环境扫描电子显微镜观察（具有能量色散微X射线分析）、力学测试和冶金分析，以了解多孔结构（大孔和微孔）、力学性能、化学成分、相组成和细胞附着行为。通过该方法制备的多孔Ti 6A 14 V具有三维小梁状多孔结构，其互连孔主要在400至700 μ m范围内，总孔隙率约为90%。抗压强度为10.3 +/- 3.3 MPa，弹性常数为0.8 +/- 0.3 GPa。MC 3 T3-E1细胞在孔内表面贴壁、铺展良好。多孔Ti6 A14 V与松质骨在互连多孔结构和力学性能方面相似，有望成为生物医学应用的有前途的生物材料。(c)2005 Wiley Periodicals，Inc. J Biomed Mater Res 73A：223-233，2005.
For the first time, a highly porous strong Ti6Al4V was produced by using a "polymeric sponge replication" method. A polymeric sponge, impregnated with a Ti6Al4V slurry prepared from Ti6A14V powders and binders, was subjected to drying and pyrolyzing to remove the polymeric sponge and binders. After sintering at a high temperature and under high vacuum, a porous Ti6A14V was produced. Optical microscopical observation, environmental scanning electron microscopy observation (with energy-dispersive micro X-ray analysis), mechanical tests, and metallurgical analyses were performed on the obtained porous Ti6A14V with regard to the porous structure (both macropores and micropores), mechanical properties, chemical composition, phase compositions, and cell attachment behavior. The porous Ti6A14V made by this method had a three-dimensional trabecular porous structure with interconnected pores mainly ranging from 400 to 700 mu m and a total porosity of about 90%. The compressive strength was 10.3 +/- 3.3 MPa and the elastic constant 0.8 +/- 0.3 GPa. MC3T3-E1 cells attached and spread well in the inner surface of pores. Being similar to cancellous, bone with regard to both interconnected porous structure and mechanical properties, the resulting porous Ti6A14V is expected to be a promising biomaterial for biomedical applications. (c) 2005 Wiley Periodicals, Inc. J Biomed Mater Res 73A: 223-233, 2005.