Morphology of the human larynx during the first five years of life studied on whole organ serial sections
Morphology of the human larynx during the first five years of life studied on whole organ serial sections
复制标题
DOI：
10.1177/000348949910800303
复制
发表时间：
1999-03-01
影响因子：
1.4
通讯作者：
Stennert, E
中科院分区：
文献类型：
--
作者：
Eckel, HE;Koebke, J;Stennert, E
人类喉在生命最初几年的形态发育至今知之甚少。本研究使用塑化的整个器官连续切片来确定婴儿喉的生长和结构。对43例1~60个月儿童的喉进行塑化。通过用金刚石带锯切割所得标本获得整个器官连续切片。然后将切片提交给计算机辅助形态测量研究。我们发现，声门下气道的大小迅速增加，在第一个2年的生活。进一步的增长遵循线性模式。粘膜衬里的相对比例也同样减少。与成年人相反。与大多数哺乳动物相比，软骨声门占声带长度的60%至75%，
The morphologic development of the human larynx during the first years of life is poorly understood to date. This study used plastinated whole organ serial sections to determine the growth and structure of the infant larynx. The larynges of 43 children 1 to 60 months old were plastinated. Whole organ serial sections were obtained by cutting the resulting specimen with a diamond band saw. The slices were then submitted to computer-assisted morphometric investigation. We found that the subglottic airway rapidly increases in size during the first 2 years of life. Further growth follows a linear mode. The relative proportion of the mucosal lining decreases likewise. In contrast to that in adults. and comparable to that in most mammals, the cartilaginous glottis accounts for 60 % to 75% of the vocal folds' length at