Quality of life of adolescents with cancer: family risks and resources.

Quality of life of adolescents with cancer: family risks and resources.
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DOI:
10.1186/1477-7525-8-63
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发表时间:
2010-06-28
影响因子:
3.6
通讯作者:
Schwartz LA
Schwartz LA
中科院分区:
医学3区
文献类型:
--
作者:
Barakat LP;Marmer PL;Schwartz LA

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本研究的目的是评估治疗强度、家庭社会人口学风险和家庭资源对102名接受癌症治疗的青少年健康相关生活质量(QOL)的相对贡献。青少年和家长完成了青少年生活质量,家庭功能和亲子关系的自我报告措施。根据父母报告的家庭社会人口统计学变量,计算了一个加性风险指数。一名儿科肿瘤学家评定了治疗强度。同时回归分析表明,在家庭功能和亲子关系的质量的角色的显着贡献的预测心理社会生活质量(父母和青少年报告),以及父母报告的青少年身体生活质量超过治疗强度的贡献。在这些回归分析中,家庭社会人口学风险对生活质量没有贡献。在其他分析中,具体的诊断,治疗类型和个人社会人口学风险变量与生活质量无关。父母和青少年对家庭功能和生活质量的评价是一致的。家庭功能,包括亲子关系的质量,是癌症治疗期间青少年生活质量的核心和潜在的可改变的抵抗因素。比依赖诊断或治疗更重要的是,在治疗早期筛查角色和关系可能是确定不良QOL结局风险的重要方面。
The goal of this study was to evaluate the relative contribution of treatment intensity, family sociodemographic risk, and family resources to health-related quality of life (QOL) of 102 adolescents in treatment for cancer. Adolescents and parents completed self-report measures of teen QOL, family functioning, and parent-child bonding. Based on parent report of family sociodemographic variables, an additive risk index was computed. A pediatric oncologist rated treatment intensity. Simultaneous regression analyses demonstrated the significant contribution of roles in family functioning and quality of parent-child relationship to prediction of psychosocial QOL (parent and teen-reported) as well as parent-reported teen physical QOL over and above the contribution of treatment intensity. Family sociodemographic risk did not contribute to QOL in these regression analyses. In additional analyses, specific diagnosis, types of treatment and individual sociodemographic risk variables were not associated with QOL. Parent and teen ratings of family functioning and quality of life were concordant. Family functioning, including quality of parent-child relationship, are central and potentially modifiable resistance factors in teen QOL while under treatment for cancer. Even more important than relying on diagnosis or treatment, screening for roles and relationships early in treatment may be an important aspect of determining risk for poor QOL outcomes.
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