Remarkable facilitation of hetero-cycloisomerizations with water and other polar protic solvents: metal-free synthesis of indolizines.
Remarkable facilitation of hetero-cycloisomerizations with water and other polar protic solvents: metal-free synthesis of indolizines.
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DOI：
10.1039/c0gc00198h
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发表时间：
2010
期刊：
影响因子：
--
通讯作者：
Sarpong R
中科院分区：
文献类型：
--
作者：
Hardin Narayan AR;Sarpong R
炔丙醇衍生物的杂环异构化反应导致中氮茚已被证明在单独的水存在下进行。这与在有机溶剂如苯、乙腈或二氯甲烷中使用与配体配对的Pt、Cu或Ag盐的先前方法相比是显著的进步。
Hetero-cycloisomerization reactions of propargylic alcohol derivatives leading to indolizines have been demonstrated to proceed in the presence of water alone. This stands as a significant advance over the previous methods using Pt, Cu or Ag salts paired with ligands in organic solvents such as benzene, acetonitrile or methylene chloride.