Guanidino compounds in serum and urine of nondialyzed patients with chronic renal insufficiency
Guanidino compounds in serum and urine of nondialyzed patients with chronic renal insufficiency
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DOI：
10.1016/s0026-0495(97)90273-0
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发表时间：
1997-09-01
影响因子：
9.8
通讯作者：
DeDeyn, PP
中科院分区：
文献类型：
--
作者：
Marescau, B;Nagels, G;DeDeyn, PP
测定了15种胍基化合物和尿素在慢性肾功能不全非透析患者血清和尿液中的水平，根据病因和肌酐清除率进行了细分。间质性肾炎、肾小球肾炎、肾炎和糖尿病肾病亚组的血清和尿液中胍基化合物水平无显著差异。根据肌酐清除率对患者进行细分，得到以下结果：（？）终末期肾功能衰竭患者血清胍基琥珀酸（GSA）和甲基胍水平（肌酐清除率
Levels of 15 guanidino compounds and urea were determined in serum and urine of nondialyzed patients with chronic renal insufficiency subdivided according to etiology and creatinine clearances, No significantly different guanidino compound levels in serum and urine were found for the interstitial nephritis, glomerulonephritis, nephrangiosclerosis, and diabetic nephropathy subgroups. Subdividing the patients according to creatinine clearance yields the following results: (?) Serum guanidinosuccinic acid (GSA) and methylguanidine levels of patients with end-stage renal failure (creatinine clearance