A STRAIGHTFORWARD METHOD FOR THE STUDY OF DRUG-INTERACTIONS - AN ISOBOLOGRAPHIC ANALYSIS PRIMER

A STRAIGHTFORWARD METHOD FOR THE STUDY OF DRUG-INTERACTIONS - AN ISOBOLOGRAPHIC ANALYSIS PRIMER
复制标题

DOI:
10.3109/10915818809014529
复制
发表时间:
1988-01-01
期刊:
JOURNAL OF THE AMERICAN COLLEGE OF TOXICOLOGY
影响因子:
--
通讯作者:
GESSNER, PK
GESSNER, PK
中科院分区:
其他
文献类型:
--
作者:
GESSNER, PK

文献摘要

被引文献

相似文献

药物相互作用的研究给研究人员带来了关于实验设计和结果解释的问题,这些问题很容易变得复杂和令人困惑。等轴线方法的优点之一是它导致了合理的实验设计,并使对所获得的结果的描述性和分析性考虑都相对简单和直接。特别是,该方法的描述性使用使得实验者能够紧凑且毫不含糊地表达所观察到的相互作用的显著特征。
The study of drug interactions presents investigators with questions about both experimental design and interpretation of results that easily can become complex and confusing. Among the advantages of the isobolographic method is that it leads to rational experimental design and renders both the descriptive and analytical considerations of results obtained relatively simple and straightforward. In particular, the descriptive use of the method is such that it permits experimenters to express compactly and unambiguously the salient features of the observed interaction.