UV PhotoVap: Demonstrating How a Simple and Versatile Reactor Based on a Conventional Rotary Evaporator Can Be Used for UV Photochemistry
UV PhotoVap: Demonstrating How a Simple and Versatile Reactor Based on a Conventional Rotary Evaporator Can Be Used for UV Photochemistry
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UV PhotoVap：演示如何将基于传统旋转蒸发器的简单多功能反应器用于紫外光化学
DOI：
10.1021/acs.oprd.8b00037
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发表时间：
2018
影响因子：
3.4
通讯作者：
Clark C
中科院分区：
文献类型：
--
作者：
Clark C
我们报告使用一个简单的旋转蒸发器作为半连续紫外光化学反应器。通过旋转烧瓶生成薄膜，实现更好的光穿透，在这项工作中，我们使用高功率汞灯来实现紫外光对分子的直接照射。以库克森二酮的分子内[2 + 2]光环加成反应和马来酰亚胺与1-己炔的分子间[2 + 2]光环加成反应为试验反应，考察了该反应器的有效性。在简单的分子内反应中获得了相当于210 g h-1的高产率，证明了反应器的可扩展性。还研究了烧瓶尺寸、反应混合物体积、硼硅或石英玻璃器皿的使用对反应的影响。
We report the use of a simple rotary evaporator as a semi-continuous UV photochemical reactor. By generation of a thin film from the rotation of a flask, better light penetration is achieved, and in this work we used high-power Hg lamps to enable the direct irradiation of molecules with UV light. The intramolecular [2 + 2] photocycloaddition of Cookson’s dione and the intermolecular [2 + 2] photocycloaddition of maleimide with 1-hexyne were used as test reactions to examine the effectiveness of this reactor. High productivities, equivalent to 210 g h–1, were obtained for the simple intramolecular reaction, demonstrating the scalability of the reactor. The effects of flask size, reaction mixture volume, and use of borosilicate or quartz glassware were also investigated.