EXPERIMENTS WITH FRACTIONATED X-IRRADIATION OF THE SKIN OF PIGS. II. FRACTIONATION UP TO FIVE DAYS.

EXPERIMENTS WITH FRACTIONATED X-IRRADIATION OF THE SKIN OF PIGS. II. FRACTIONATION UP TO FIVE DAYS.
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对猪皮肤进行分段 X 射线照射的实验。

DOI:
10.1259/0007-1285-38-448-278
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发表时间:
1965
期刊:
The British journal of radiology
影响因子:
--
通讯作者:
J. A. Silvester
J. A. Silvester
中科院分区:
--
文献类型:
--
作者:
J. Fowler;D. K. Bewley;R. L. Morgan;J. A. Silvester

文献摘要

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用1、2、2、3和5次照射,分别在1、5、2、3和5天内照射一头猪的15个野。记录长达80或100天的皮肤反应,以便评估产生相同反应的剂量。分析了早期、中期和晚期反应的三种损伤程度。例如,对于以上列出的组分,在30-85天内产生一个反应水平的剂量分别为2,050、2,560 - 2,750、2,750、3,360和4,060拉德。“DQ”=(Dn-D1)/(n -1)的相应值很高,为500-700拉德。分数越多,(Dn − D1)/(n − 1)的值越小。对两头猪进行辐照,以研究“相互邻近”效应。它被发现是小的领域安排使用,但猪皮肤的敏感性增加,在背腹方向和纠正有时是必要的。用成对的相等剂量(间隔0至24小时)对两头猪进行辐照。观察到的恢复模式与发现的相似...
Fifteen fields on one pig were irradiated with 1, 2, 2, 3 and 5 fractions in 1, 5, 2, 3 and 5 days respectively. Skin reactions were recorded up to 80 or 100 days, so that the doses which produced equal reactions could be assessed. Three degrees of damage were analysed for early, medium and late reactions. As an example, the doses to produce one level of reaction over 30–85 days were respectively 2,050, 2,560–2,750, 2,750, 3,360 and 4,060 rads for the fractions listed above. The corresponding values of “DQ” = (Dn — D1)/(n —; 1) were high, 500–700 rads. The values of (Dn − D1)/(n − 1) became smaller with larger numbers of fractions. Two pigs were irradiated to investigate the “reciprocal vicinity” effect. It was found to be small for the field arrangements used, but the sensitivity of pig skin increased in the dorso-ventral direction and corrections were sometimes necessary. Two pigs were irradiated with pairs of equal doses separated by 0 to 24 hours. A recovery pattern was observed similar to that found ...