THE EFFECTS OF SPECIFIC MEDICAL CONDITIONS ON THE FUNCTIONAL LIMITATIONS OF ELDERS IN THE FRAMINGHAM-STUDY
THE EFFECTS OF SPECIFIC MEDICAL CONDITIONS ON THE FUNCTIONAL LIMITATIONS OF ELDERS IN THE FRAMINGHAM-STUDY
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DOI：
10.2105/ajph.84.3.351
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发表时间：
1994-03-01
影响因子：
12.7
通讯作者：
KANNEL, WB
中科院分区：
文献类型：
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作者：
GUCCIONE, AA;FELSON, DT;KANNEL, WB
目标。这项研究的目的是确定老年人特定的医疗条件与功能任务限制之间的联系；比较不同医疗条件下的残疾风险，控制年龄、性别和合并症；并确定每种条件下的残疾比例。研究对象为弗雷明翰研究队列中的709名非住院男性和1060名女性(平均年龄73.7±6.3岁)。研究确定了10种疾病：膝骨性关节炎、髋部骨折、糖尿病、中风、心脏病、间歇性跛行、充血性心力衰竭、慢性阻塞性肺疾病、抑郁症状和认知障碍。调整后的优势比被计算在七个功能活动中对人类协助的依赖。在所有七个任务中，中风与功能受限显著相关；抑郁症状和髋部骨折与五个任务中的限制相关；膝骨性关节炎、心脏病、充血性心力衰竭和慢性阻塞性肺疾病分别与四个任务中的限制相关。一般来说，中风、抑郁症状、髋部骨折、膝骨性关节炎和心脏病在非住院老年男性和女性中造成的身体残疾比其他疾病更多。
Objectives. The purpose of this study was to identify associations between specific medical conditions in the elderly and limitations in functional tasks; to compare risks of disability across medical conditions, controlling for age, sex, and comorbidity; and to determine the proportion of disability attributable to each condition.Methods. The subjects were 709 noninstitutionalized men and 1060 women of the Framingham Study cohort (mean age 73.7 +/- 6.3 years). Ten medical conditions were identified for study: knee osteoarthritis, hip fracture, diabetes, stroke, heart disease, intermittent claudication, congestive heart failure, chronic obstructive pulmonary disease, depressive symptomatology, and cognitive impairment. Adjusted odds ratios were calculated for dependence on human assistance in seven functional activities.Results. Stroke was significantly associated with functional limitations in all seven tasks; depressive symptomatology and hip fracture were associated with limitations in five tasks; and knee osteoarthritis, heart disease, congestive heart failure, and chronic obstructive pulmonary disease, were associated with limitations in four tasks each.Conclusions. In general, stroke, depressive symptomatology, hip fracture, knee osteoarthritis, and heart disease account for more physical disability in noninstitutionalized elderly men and women than other diseases.